How Effective Is Chemotherapy for Cancer?

Cancer chemotherapy is a way to treat cancer. The ideal chemotherapy drug should only target and destroy cancer cells, and have no toxic side effects on normal cells. However, this drug does not exist; killer cells in cancer cells and normal cells There is a narrow therapeutic index range between them. Chemotherapy (hereinafter referred to as chemotherapy) can also be cured for a single tumor with indications (i.e. chorioepithelial cancer, hair cell leukemia, chronic lymphocytic leukemia). However, it is more commonly used to form a combined drug regimen based on the different mechanism of action of the drug, the intracellular site of action and toxicity (to reduce the potential for toxicity and synergy), which can significantly improve the cure rate (such as acute leukemia, bladder). And testicular cancer, Hodgkin's disease, malignant lymphoma, small cell lung cancer, and nasopharyngeal cancer).

Cancer chemotherapy

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Cancer chemotherapy is a way to treat cancer. The ideal chemotherapy drug should only target and destroy cancer cells, and have no toxic side effects on normal cells. However, this drug does not exist; killer cells in cancer cells and normal cells There is a narrow therapeutic index range between them. Chemotherapy (hereinafter referred to as chemotherapy) can also be cured for a single tumor with indications (i.e. chorioepithelial cancer, hair cell leukemia, chronic lymphocytic leukemia). However, it is more commonly used to form a combined drug regimen based on the different mechanism of action of the drug, the intracellular site of action and toxicity (to reduce the potential for toxicity and synergy), which can significantly improve the cure rate (such as acute leukemia, bladder And testicular cancer, Hodgkin's disease, malignant lymphoma, small cell lung cancer, and nasopharyngeal cancer).

Effect

Chemotherapy drugs that have proven effective in vitro but not effective in vivo have led to extensive research on drug resistance. One of the known mechanisms of multidrug resistance is due to the presence of some genes in patients' cancer cells that limit the drug's stay and function. Studies trying to change this resistance have yet to bear fruit.