Is it safe to take metoclopramide during pregnancy?
Study on the use of metoclopramide during pregnancy suggests that the drug seems safe for use during pregnancy, although multiple controlled data may be necessary for this confirmation. American food and drug administration (FDA) classifies it as a drug of category B, suggesting that no adverse effects have been observed in animals. Medical scientists believe that it does not increase the risk of congenital defects on the basis of retroactive review of medical records for the patient, exploring pregnancy and results for women who have taken during pregnancy, serious ethical problems need to be considered. Adult approval of clinical trials can freely participate and the studies can be stopped as soon as serious adverse effects appear. Fruits cannot apply for participation in clinical trials and fetal damage may not occur only after giving birth and deliiver. Much data is therefore based on a combination of animal tests and use in limited populations of women who decide to take the risk of drugs because the benefits seem to bethat the chances of the problem prevail over the benefits.
Metoclopramide operates to dopamine receptors in the central nervous system. It inhibits vomiting and increases the speed of stomach emptying. The doctor may prescribe metoclopramide during pregnancy to treat severe vomiting, which is most often a problem in the first trimester. The first trimester is also a period of critical concern with the development of the fetus, because at this stage of pregnancy a large part of the nervous system frame is laid. Medicines that affect the central nervous system are a potential cause of concern, especially when they easily pass over the placenta, as does metoclopramide.
Thereview of the patient's results shows that there is no increase in the risk of congenital defects and other complications associated with the use of metoclopramide during pregnancy during any trimester. These studies also show that neurological development for children born to mothers who use the oneThe medicine seems to be doing normally. This suggests that the use of metoclopramide during pregnancy does not damage the developing nervous system.
However, there are concerns about the use of this drug during breastfeeding. The drug is excreted by breast milk and can potentially cause complications for the developing child. It can also cause symptoms such as uncontrolled tremor in patients taking a medicine, which may be the worry of pregnant women who consider metoclopramide in pregnancy to control nausea.