Is there a connection between amitriptylin and weight gain?
There is a strong and established connection between amitriptyline and weight gain. As one of the most prescribed and effective antidepressants since its development in 1961, the drug has been studied considerably. Tricyclic antidepressants (TCA), such as amitriptylin, may affect metabolism, worsen carbohydrates of desire and increase appetite in many people. It seems that amitriptylin causes the most increasing weight of all TCA. In some people, it can also help with a bed wetting, schizophrenic symptoms and anxiety. Despite its efficiency record, amitriptylin has side effects, which include drowsiness, dry mouth and weight gain. For some patients, they may be sufficiently problematic that they are looking for newer classes of antidepressants that have less or tolerant side effects. For many, it is sufficient to increase Vázodřita itself since the takeover of TCAS. The drug can increase appetite and desire for simple carbohydrates and sugar. Many patients reported extreme desires while others do not experienceNo change in appetite. These desires may be disturbing for some patients, especially those who are already fighting weight gain due to diabetes or other health problems.
There is a possibility that amitriptylin can reduce metabolism, causing weight gain without the corresponding increase in caloric intake. Since TCA has anticholinergic effects similar to anithistamines, they can interfere with histamine receptors. Drugs that work in this way often have weight gain as a side effect.
It seems that the connection between amitriptyline and weight gain is a dose depending on between 10mg and 150 mg. Patients who use higher doses tend to gain weight faster than those taking lower doses. Also, those who take the medicine for a longer period of time tend to continue to gain weight throughout the treatment. In one study fromPatients were between 1 and 3 pounds (2 and 7 kilograms) per month of TCAS treatment. It was not specified which drug was responsible for weight gain, although amitriptylin and imipramine are usually TCA most associated with gaining weight.
It should be noted that many patients do not experience a connection between amitriptyline and weight gain. Some notice weight increases, but either decide to be small enough to be tolerable, or that the benefits of treatment outweigh any side effect. In addition, if the problem is a pound, the patient should consult his doctor that he has been shut down or modified the dose. In many cases, the patient must only stop taking amitriptylin and the weight gain stops.