What factors affect the sufficient dose of acycloviru?

Acyclovir, also sold under the Zovirax & Reg brand, is an antiviral prescription drug used to treat viruses in the Herpes family. Its development was considered a revolutionary discovery that pharmacologist Gertrude B. Elion won the Nobel Prize in Medicine. The drug is poorly absorbed orally, requires a large amount to be received, or that it is cooperated with the Valaciclovir drug to achieve sufficient dose of acyclovirus. Other factors that may affect the recommendations of acyclovirus doses are the age of the patient to be treated as well as its level of renal and immune system function.

At the beginning of treatment for herpes simplex in a typical adult, 200 mg collected by mouth five times a day for 10 days recommends manufacturers. Alternatively, a dose of 400 mg can be taken three times a day. For herpes simplex affecting lips, the dose can be used for just five days.

Whiledet at the age of 12 and older may be followed by a recommendation for an adult acycloviru dose, they shouldThe age of three months and 11 years use 10 to 20 mg per kilogram of body weight four times a day. In infants less than three months, the dose of acycloviru 10 mg per kilogram should be administered intravenously every eight hours for 10 to 21 days. Premature infants should not receive more than 10 mg intravenously every 12 hours.

oral dose of acyclovirus for adult patients with reduced immune function is the same as in patients with normal immune function, although drugs can be taken up to 14 days. Alternatively, medicines can be administered intravenously at a dose of 5 mg/kg every eight hours for the same time. In children aged 12 years and older, standard adult dosages can be used, while those aged 3 months and 11 years old should use 5 to 10 mg per kilogram of body weight.

One of the risks of acyclovirus in patients with reduced kidney function is renal failure. Before the patient endangered failureThe kidneys receive this medicine, should consult with the dosing chart for acyclovir to determine the lowest possible sufficient dose for the treatment of its condition. Dosage adjustments for renal impairment are comparable to adults in children. However, the reduced function of the liver does not affect the metabolism of the drug and does not require any regulations of the recommended dose.