What factors affect a sufficient dose of loperamide?
Loperamide, commonly known as IMODIUM®, is a popular over -the -counter medicine for the treatment of acute diarrhea. The lower dose of loperamide is sometimes recommended as treatment of chronic diarrhea. Whenever you enjoy loperamide, the lowest effective dose should be used. In addition to long -term condition, age is the most important factor in determining the appropriate initial dose of loperamide for administration.
In the treatment of acute diarrhea, the recommended dose of loperamide for the first day of 4 mg given orally with another 2 mg after each free bowel movement. Improvement is generally seen within 48 hours. The total dose of loperamide should not exceed 16 mg per 24 hours.
The recommended dose in the treatment of the same condition in children between eight and 12 years is initially only 2 mg, while maintenance doses do not exceed 6 mg per day. In children aged six and eight years, the maximum daily dose should not exceed 4 mg. Between children for two and five years should initially receive only 1 mg and not more than 3 mg per day. After a single day of treatment, the drug should be given only after free afterThe intestinal movement, while the total daily dose of the patient does not exceed 1 mg per kg of body weight.
In the treatment of chronic diarrhea, adults should first use a standard dose for acute diarrhea to achieve a breakthrough level of treatment. The dose of loperamide should then be reduced to the lowest possible level that is effective in checking the patient's symptoms. It has not been shown that doses longer than 16 mg daily offer no increased efficiency in the treatment of chronic diarrhea, while the most common doses of effective maintenance are between 4 mg and 8 mg per day. No safe and effective dose of loperamide has been determined for the treatment of chronic diarrhea in pediatric populations.
due to the incremental risk of loperamide, when it undergoes at high doses or for a long time, it is important to administer as little this drug as possible. Although generally considered a safe medicine, some side effects of loperamide may include fromIdrate, disorientation, drowsiness, constipation, itching of mild rashes or mild stomach pain. However, if these conditions become serious or are accompanied by a deterioration of the condition, it is possible that they are signs of serious allergic reactions. The use of loperamide should be immediately terminated in patients who complained of such symptoms.