What factors affect sufficient dose of nitroglycerin?

"nitroglycerin" or "nitroglycerin" (NTG) is a drug used to treat chest pain, which is often referred to from medical point of view as angina or angina. This medicine is one of the heart nitrate drugs used to treat angina with coronary arteries to increase blood and oxygen flow into the heart muscle. Nitroglycerin is available in almost every conceivable form, but is the best known publicly for its small sublingual tablets that are located and absorbed under the tongue. A sufficient dose of nitroglycerin is one that releases angina of the patient, prevents heart damage due to low oxygenation or ischemia of myocardium and prevents disproportionate side effects. Due to the number of ways of administered, the adequate dose of nitroglycerin, the degree of coronary artery blocking, the degree of stress placed on the heart that caused an angom episode, and other problems also differ according to the feed route.

is a feeding route. Nitroglycerin can be taken in various ways such as ointment, patches, sublingually, orally in prolonged capsules, orally or nasty in aerosol form and intravenously. All these types of nitroglycerin administration are used to increase cardiac perfusion and oxygenation by coronary arteries, although some routes are used in different circumstances. Intravenous nitroglycerin, prolonged release capsules, ointments and patches are used on a prophylactic basis to prevent aginal attacks. Aerosol nitroglycerin sublingual and nasal aerosols are used to treat and relieve acute angina episodes Based on the required base.

Another factor that affects whether a given dose of nitroglycerin effectively releases acute angina is the extent of coronary artery blocking and the number of arteries affected by coronary arteries. Higher oral doses may be essential for patients with advanced coronary arteries to make the heart be performed with adequate blood andoxygen. The degree of stress associated with the inducing angineal episode may also be a factor in determining sufficient dose of nitroglycerin. For example, walking on the flight of the stairs carrying a grocery bag requires greater effort than watching a television show in a chair and may require a higher or repeated dose of nitroglycerin than Angina occurs at rest.

doses of sublingual nitroglycerins necessary to relieve angina are also affected by the age of pills or exposure to the drug of heat or light. Previous or repeated use of nitroglycerin also reduces its efficiency because the drug has less effect on coronary arteries. Geriatric patients are considered to be a higher risk of side effects of nitroglycerin, especially hypotension, and may use smaller therapeutic doses. Finally, nitroglycerin interacts with many differences of drug types. These interactions often require dosing adjustment for one or more medicines.