What factors affect the dosage of acetylcysteine?
Acetylcysteine is a medicine with many uses, from mucus breaking to the replacement of certain sulfur molecules lost in autism, to reversal of an overdose of acetaminophene. Many factors may affect the dosage of acetylcysteine, but the main factor is the condition used for treatment. Other factors, such as the patient's age, body weight and the presence of liver or kidney damage, could affect how much of this drug is also used on the individual. The initial dose load of 150 milligrams (mg) per kilogram (kg) is administered in 200 milliliters (ml) of physiological solution during the first hour. Furthermore, 50 mg per kg is administered in the next four hours. Finally, 100 mg per kg of this medicine is given in 1000 ml of solution for 16 hours, a total of 300 mg per kg for 21 hours.
Children up to £ 88 (40 kilograms) can use concentrated dosage of acetylcysteine. Mg per kg used to treat children in overdose is the same as in adults. The main difference is that there is a lot of liquid in childrenHalf and the solution focuses even more.
Some forms of cystic fibrosis can lead to thick mucus that is difficult to clean. This medicine is sometimes used to disintegrate mucus and facilitate coughing. A high dose of acetylcysteine may be given 600 mg, due to three times a day. Research has shown that the use of this drug at this dose promotes a higher level of survival and can help these patients develop pneumonia.
For more frequent use, for example in the treatment of autism or overload, this drug is administered in much smaller quantities. Acetylcysteine for this purpose comes in 10 ml and 30 ml bottles 10% and 20% solutions. In this form, 1 to 10 ml of both solutions can be injected or inhaled at once. In general, slightly higher doses are also needed a stronger 20% solution when this drug is evaporated by a sprayer and inhaled.
Some studies believe that kidney or liver damage might have a dopaD on the ability of this medicine to clean from the body. However, many doctors do not reduce acetylcysteine dosing in individuals with liver damage. Doctors may decide to reduce the dose in patients with kidney problems if they feel that these problems would prevent the will of the drug.