What factors affect vardenafil dosing?
vardenafil, also known under the Levitra brand, is used to treat erectile dysfunction. While the initial dose of vardenafil is usually recommended 10 mg, collected an hour before sexual activity, it can increase this dose or reduce several factors. Variables such as age, health and other patient medicines may require the dose to reduce how unpleasant side effects can. If the effects of low initial dosing of Vicedenafil are unsatisfactory, the dose may be adjusted up. According to the Vardenafil manufacturer, the frequency of dosing should not be more than a day.
vardenafil is very similar to both in its activity and in the chemical structure as citrate Sildenafil, a drug sold under the Viagra & Reg. Both Vardenafil and Sildenafil citrate are members of the drug class known as inhibitors of phosphodiesterase type 5 (PDE5). The risks of vardenafil are almost the same as in other drugs in this family, including side-effects such as nausea and rarely, photocitation, back pain, abdominal painIcha, blurred vision, face edema, eye pain, racing heart, low blood pressure, itching, pain and pain or painful erection lasting more than four hours. Serious but rare side effects include sudden deafness or heart attack. Since a higher dose of vardenafil may increase the incidence and severity of these side effects, it is preferable to use a low dose to start treatment.
Patients taking other medicines should discuss possible medicines with their doctor before entering vardenafil, because many interactions have the potential to be serious or fatal. The drug interaction between nitrates and drugs can lead to a potentially fatal drop in blood pressure. Alfa blockers alfuzosine, doxazosin, prazosine, tamsulosin and terazosin, sometimes used in high blood treatment, also observed that the pressure or benign prostate hyperplasia worsens blood pressure and reduces the effects of vardenafil. Many medicines forEdpis against error can increase the blood -river medicine level, causing to adjust the dosing of vardenafil down. If the patient uses medicines for heart arrhythmia quinidin, prokainamide, amiodarone or sotalol, further erectile dysfunction should be used because the combination of these vardenafil drugs can lead to extremely dangerous heart condition known as QT prolongation.
If the administration of vardenafil to a patient who uses medicines that affect the enzyme of the liver cytochrome P450, it may be necessary to adjust the dose for compensation. Due to the role of this liver enzyme in the metabolism of the drug, lower initial dosing vardenafil should be used in patients with reduced liver function. In many of these patients, the initial dose may be up to 2.5 mg be sufficient.