What is serm?
SERM is a shortcut for selective modrogen receptor modulator . SERMs are medicines that can be used in the treatment or prevention of certain breast cancer forms. Not treating all forms of breast cancer, but are specifically focused on the type called hormonal breast receptor cancer. In this type, cancer cells have receptors for estrogens or progesterone and can increase when they come into contact with these hormones, which makes the use of SERM to block this action.
The body has estrogen receptors in many places. Breast and uterus tissue contain them, as well as cells in the bones. One disadvantage simply shutting down hormones is that bone mass can begin to deteriorate, how often it does when menopause is achieved.
The way around this is to find a selective blocking method of some receptors in hormone receptors and ignoring others. SERM only achieves a focus on the uterus and brush and avoiding the inhibition of acceptance of estrogen in other parts of the body. TowerIt is that receptors in different parts of the body are slightly different, so it is possible to design medicines that can be selective.
When breast cancer is present, SERM as Tamoxifen or Evista® may be considered as part of treatment. It is not always the best choice and doctors can recommend a different direction. These drugs are not particularly useful if cancer does not have hormonal receptors. Sometimes the treatment of SERM continues several years after the treatment of cancer as a preventive. In other cases, women or men with high genetic risk factors for breast cancer take one of these drugs to prevent its occurrence.
Many people praise Sermes as miraculous drugs providing both prevention and possible treatment for some forms of deadly disease. They certainly deserve Prais, but come with a high side effect profile, which can make them difficult. These include a number of symptoms that mimic menopause, increased risksKoy, increasing the risk of uterine cancer, loss of libido and depression. This last may be difficult to treat because many antidepressants appear to interact with tamoxifen.
The potential for serious side effects when using SERM definitely exists. Patients are recommended to thoroughly examine risks and benefits and understand which side effects require emergency treatment. Although some people experience more serious side effects on these drugs, people who use SERM can also experience small or no disorders. The most important thing is that SERM can have much to significantly reduce the risk of breast cancer and statistically, it has been shown that these drugs improve survival results combined with different treatment.