What Is an Antithrombotic?

Thrombosis is a small piece of blood formed on the surface of the inner wall of the cardiovascular system by spalling or repairing. In variable flow dependent patterns, a thrombus consists of insoluble fibrin, deposited platelets, accumulated white blood cells, and trapped red blood cells.

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Thrombosis is

Cardiac and vascular endometrial injury

TCM has the idea of "not treating the disease".

Antithrombotic drugs can be divided into

1. Softening, dissolving and absorbing: small blood clots can be completely dissolved and absorbed; large blood clots can be partially dissolved and softened, and easily formed by the impact of blood flow.

1. White thrombus occurs in areas where blood flow is fast (such as arteries, ventricles) or when blood flow is rapid during thrombosis (such as the beginning of venous mixed thrombus, which is propagating thrombus head. Under the microscope, the white thrombus is mainly composed of many platelet-shaped trabeculae aggregated on the surface. Many neutrophils adhere to the surface, forming a layer of white blood cells, presumably due to the chemotaxis of cellulose disintegration products. Platelet trabeculae form a network of cellulose due to the action of activated coagulation factors, and the network contains a small amount of red blood cells. It is gray-white to the naked eye, with rough and corrugated surface, hard, and tightly connected to the blood vessel wall.

thrombus

2. The main part (body) of a continuous thrombus in a mixed thrombus vein is red and white stripes, which is a mixed thrombus. The formation process is: the platelet-based trabecula-based thrombus continues to grow so that its downstream blood flow forms a vortex, thereby generating another platelet-based thrombus, and the blood between the two is coagulated, becoming red blood cells as The main thrombus. If alternating, it will become mixed thrombosis. During mitral stenosis and atrial fibrillation, a spherical thrombus can be formed in the left atrium; this kind of thrombus and the thrombus in the aneurysm can be seen in alternating gray-white and red-brown layered structures, called lamellar thrombosis, which is also mixed thrombus.

3 Red thrombus occurs after the blood flow is extremely slow or even stopped, and its formation is the same as that of extravascular coagulation. Therefore, the red thrombus is seen in the mixed thrombus that gradually increases and blocks the lumen. After the local blood flow stops, it often forms the tail of the continuous thrombus. Under the microscope, the cellulose mesh is filled with blood cells distributed like normal blood. The naked eye is dark red. Fresh red blood clots are moist and have some elasticity. Old red blood clots become dry, brittle, lose elasticity due to water absorption, and easily fall off and cause embolism.

4 This kind of thrombus occurs in small blood vessels of the microcirculation and can only be seen under a microscope. Therefore, it is also called microthrombus. It is mainly composed of cellulose and is found in diffuse intravascular coagulation.