What Is Baclofen?

Baclofen is a derivative of gamma-amino acid. Can inhibit the release of excitatory amino acid neurotransmitters, reduce the excitability of spinal monosynaptic and multisynaptic reflexes, reduce the release of substance P and calcium influx, thereby alleviating myotonia and painful spasms.

Basic Information

1. For skeletal muscle spasm caused by multiple sclerosis.

2. For infectious, degenerative, traumatic, tumor or spontaneous spinal cord disease caused by unknown spinal cord diseases, such as: spastic spinal palsy, amyotrophic lateral sclerosis, syringomyelia, transverse myelitis, trauma Paraplegia or paralysis, spinal cord compression, spinal cord tumors, and motor neuron disease.

3. For brain-derived muscle spasm, such as: muscle spasm caused by cerebral palsy, cerebral palsy in children, stroke and cerebrovascular accident, brain tumors, degenerative encephalopathy, meningitis, and craniocerebral trauma.

4. Can also be used for urinary retention caused by external sphincter spasm.

Oral: Start at 5 mg / time, 3 times / day, increase the dose every 3 days, and increase 5 mg each time, until the required dose, usually the appropriate dose is 75 mg / day, depending on the condition, it can reach 100 to 120 per day Mg. Children generally 4 times a day, the recommended maintenance dose: 12 months to 2 years, 10 to 20 mg / day; children 2 to 6 years: 20 to 30 mg. Children 6 to 10 years: 30 to 60 mg (maximum 70 mg).

Overdose is mainly manifested as central nervous system depression and convulsions. Use with caution in patients with mental disorders, peptic ulcers, and high sphincter tone. It should be gradually reduced when stopping the medicine.

Overdose is mainly manifested as central nervous system depression and convulsions. It should be gradually reduced when stopping the medicine.

Use with caution in patients with mental disorders, peptic ulcers, and high sphincter tone.

Note: The above content is only for introduction, the drug use must be carried out by a regular hospital under the guidance of a doctor.