What are burkinje cells?

Barkinje cells are a type of neuron found in the cerebral cortex on the brain. It is one of the largest neurons and are responsible for most of the electrochemical signaling in the cerebellar. The cells of Purkinje take their name from Czech anatomist Jan Evangelista Purkyně, who discovered them in 1837. They are densely stacked into the cerebral cortex, where they intersect with numerous parallel fibers resulting from the granules of the cerebellar cortex. Purkinje neurons are classified as inhibitory because they release the neurotransmitter GABA, which binds to receptors that operate inhibiting or reducing neuron shooting speed. They send inhibitory projections to dense neural clusters in the middle of the cerebellar called deep cerebellar core.

Purkinje and Cerebellum cells are essential for the motor function of the body. Disorders involving burkinj cells usually negatively affect the patient's movement. Purkinje cells can be affected by genetic and obtained disorders.

genetic disorders affecting burkinj cells include cerebellar hypoplasia, autism, telangiectasia and Niemann ataxia choose the type of C disease. In brain hypoplasia, a patient with insufficiently developed mose was born, either because the bunches have never fully evolved into speech. In other genetic disorders affecting brains, symptoms may not occur only several years after birth, after which they may deteriorate. Niemann chooses the type of C disease sometimes causes death within a few months after birth and in other cases does not manifest until adolescence. All cerebellar sexual disorders are characterized by reduced motor function, such as abnormal walking, seizures, involuntary eye movement or uncoordinated limb movement.

neurons burkinje can also be damaged by disorders developed later in life, such as autoimmune disorders, including immuno -deficiency syndrome (AIDS) and neurodegenerative disordersIirod to genetic. They are also subject to damage by toxic elements in the environment. Excessive alcohol or lithium use can cause cerebral degeneration. Stroke can also damage neurons burkinje.

There is no medicine for any disorders affecting neurons of burkinje. Any treatment is therefore supportive and symptomatic. In children born with brain disorders, speech therapy, ergotherapy and physical therapy may be useful in improving the child's motor skills.