What Is Hepatocyte Growth Factor?

Hepatocyte growth factor (HGF) was discovered as a substance that can stimulate the proliferation of liver cells. Later, it was discovered that HGF can also act on a variety of cells such as epithelial cells, hematopoietic cells, and vascular endothelial cells. Multifunctional factors for cell growth, movement and morphogenesis. Through paracrine or autocrine mechanisms, and through the interaction of epithelial-mesenchyme, it plays an important role in embryogenesis, wound healing, angiogenesis, tissue and organ regeneration, morphogenesis and carcinogenesis.