What is the pathophysiology of lung cancer?

Pathophysiology of lung cancer is a complicated problem. Genes that are affected by the pathogenesis of lung cancer are proteins that participate in various processes, including growth and differentiation of cells, cell cycle processes and angiogenesis, which is the formation of new blood vessels. Proteins also play a role in tumor progression, immune regulation and apoptosis. Since the participating cells are complex and have a wide range of functions, it is difficult to determine the pathophysiology of lung cancer.

It is estimated that up to 90% of all lung cancer are the result of cigarette smoking. Lung cancer corresponds to most of all cancers around the world, in men and women. In addition to smoking cigarettes, other tobacco products such as tobacco and cigars contribute to the pathophysiology of lung cancer. Other toxins such as Radon, Arsen and asbestos seem to play a role, as well as second -hand smoke. The World Health Organization (WHO) estimates that approximately 1.2 million cases of cancer around the world are caused by Rakovinou lungs. A high fat diet has been found to contribute to increased risk. On the contrary, a diet with a high content of fruits and vegetables was associated with reduced risk.

Labe rctors are generally classified as small cell lung cancer (SCLC) or non -masococcan lung cancer (NSCLC). Nicer lung cancer is approximately 85% of all lung cancers. NSCLCs are further divided into three subcategories: adenocarcinoma, large cell carcinoma and spinocellular cell carcinoma. Adenocarcinoma is the most common type of NSCLC among non -smokers. SCLC is lung cancer most associated with smoking, and almost all patients who have a smoking history.

Regardless of the classification, cancer that occurs in the lungs is the result of normal mucosal cells mutating into malignant cell structures. Pathophysiology of lung cancer is a very complex course, influenced by many factors. Progress is doneIn understanding this very complex pathophysiological system and since risk factors are identified and preventive measures are carried out, the knowledge and ability of the medical community prevention, diagnostics and treatment of lung cancer is also increasing. Once some processes that go through genes and cells have been recognized, and the pathophysiology of lung cancer is better understood, therapies and timely detection will be possible.