What is reciprocal translocation?

reciprocal translocation is an anomaly of chromosome, where two chromosomes from different couples exchange part of their genetic material with each other. For example, 13. Chromosome could replace genetic material with 16 chromosome. In many cases, translocations do not cause health problems, but can lead to fertility. Some types of translocations have been associated with health problems, such as increased susceptibility to cloak cell lymphoma in people who have a mutual translocation between the 14th and 11th chromosome. In healthy meiosis, chromosomes exchange only genetic material with chromosomes in the same pair. In mutual translocation, the material jumps between chromosomes in separate pairs and creates so -called derivative chromosomes. Depending on the material, the cell cell may be able to successfully connect with another cell cell and create a zygot that becomes a translocation carrier, or the cell can be unnecessary for reproduction, making it infertile.

In balanced mutual translocation, the same amount of material is interchanged between chromosomes. Unbalant translocations include segments of different lengths from each chromosome. It is more likely to cause infertility and are also more likely to lead to health problems; If one chromosome is shortened in the pair and the other has a harmful gene, it can expresses the gene because the corresponding healthy part of the chromosome to rewrite is missing.

Some mutual translocations are associated with congenital disorders, especially in cases where people with translocation reproduce and pass on defective chromosomes to their descendants. Others may not be recorded and some cases may even contribute an evolutionary advantage. The ability to replace and mix genetic material during sexual reproduction was valuable for a wide range of species and occasional translocations can provide an advantage.

Symptoms of reciprocal translocation may be revealed during genetic testing when poisonEN or more chromosomes may seem abnormal or there is a sequence on a chromosome that does not obviously do not belong. People with translocation who have difficulty in concept can discuss their possibilities with a fertility specialist. Assisted reproduction can be used to successfully fertilize the egg, or options such as donor or sperm eggs need to be considered to achieve a healthy pregnancy.