What is a dopamine transporter?
Dopamine transporter is a type of protein that actively transports a neurotransmitter dopamine in nerve synapses. When dopamine moves from the synapse to the neuron, it is a dopamine transporter, which is usually responsible for performing this function. In this way, the dopamine signal is effectively informed by the neuron. For this reason, dopamine transporter disorders are accused of several psychological disorders, including clinical depression, alcoholism and bipolar disorders.
As with all proteins, there is a specific location in the human genome that contains a dopamine protein code. It is located on the fifth chromosome and can sometimes be subjected to a state called genetic polymorphism. This will cause more protein to be created by the transporter dopamine than it would normally be healthy. Too much protein could lead to premature cleaning of dopamine from the synapses, and this would be a genetic predisposition to disorders such as the above.
Dopamine is one of the main neurotransmitters in the brain and is particularly important for feelings such as motivation and reward. Attention and learning are also affected as well as movement, mood and sleep. It is easy to understand how even a minor imbalance in a dopamine transporter can have significant consequences in a person's life. As a person ages, less dopamine is produced in the body cells. As dopamine levels decrease, dopamine transporter levels also decrease proportionally to compensate for this difference.
Several types of drugs can work on the blocking of dopamine transporter by preventing operation as normal. Cocaine and amphetamines fall into this category, as well as some drugs used as antidepressants such as bupropion hydrochloride. All of these medicines reduce the speed at which dopamine is removed from the synapse, and lets them transmit the signals again and again. The pleasant feelings that all these drugs bring are with the bestMore likely a direct consequence of how they act on neurotransmitters.
Some disorders related to dopamine are not the result of excessive activity of the dopamine transporter, but due to the lack of dopamine itself. When administered as a drug, dopamine affects a sympathetic nervous system in a way, such as an increase in heart rate, but in this form it cannot enter the brain through the barrier blood Emita. For this reason, other drugs that affect the dopamine transporter, or supplied dopamine in other ways, to treat conditions that are related to dopamine deficiency rather than the excess of the dopamine transporter.