What Is a Central Giant Cell Granuloma?

Giant cell granuloma (giant cell granuloma) is also called giant cell reparation granuloma (GCRG). In 1953, Jaffe introduced giant cell repair granuloma (GCRG) for the first time. He believed that GCRG is a rare non-neoplastic benign lesion, which is a proliferative repair response caused by traumatic intraosseous hemorrhage and is locally invasive. Jaffe's contribution is to propose that GCRG is a non-tumorous disease. This view has been accepted by most scholars, but he has questioned the term trauma and repair because not all patients have a history of trauma, and some even suggested that In the term giant cell repair granuloma, delete "repair". Since Jaffe reported GCRG of the mandible for the first time, there have been sphenoid bone, ethmoid bone, skull base, temporal bone, orbital bone, and craniofacial bone. Case reports of small bones in the hands and feet and long bones in the limbs. The incidence of GCRG is very low, accounting for about 7% of benign bone lesions. Head and neck GCRG is rarely reported for the following reasons: First, the disease is indeed rare; second, people's understanding of the disease is not comprehensive enough, and further research is needed.

Giant cell granuloma

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Giant cell granuloma, also known as giant cell repair

Occurs in children and young people, with 86% of cases reported before the age of 25. Occurs in

Although GCRG is a non-tumor benign lesion, it is locally invasive and should be actively treated. At present, there are mainly the following treatments.

1. GCRG has a tendency to relieve itself, so some people think that

It should be light, eat more fruits and vegetables, match the diet reasonably, pay attention to sufficient nutrition, and follow the doctor's advice.

There is no effective preventive measure for this disease. Early detection and early diagnosis are the key to the prevention and treatment of this disease.

Is a tumor-like lesion

Should be

Laboratory inspection:

Visible lesions like jaws

Can cause tooth displacement, movement and root absorption.

The recurrence rate of GCRG is 10% to 15%, and it has also been reported as 69% to 75%, but no local and distant metastasis has been reported.

In short, from the current point of view, for GCRG, complete resection of the lesion is an effective treatment method, and follow-up should be performed regularly after the CT review.