What Is Anaplastic Carcinoma?

Undifferentiated thyroid cancer is the most malignant type of thyroid cancer, with an incidence rate of about 10-15% of all thyroid cancers. Older and weaker people are more common, and the disease is rapid. Systemic metastases can occur at an early stage. It is generally considered that white thyroid Benign tumor or low malignancy. Undifferentiated carcinoma (also known as anaplastic carcinoma or sarcomatoid carcinoma) is rare. It occurs more than 40 years of age. It is more common in women. It grows quickly and infiltration can occur early. And metastasis, high degree of malignancy, and poor prognosis.

Undifferentiated thyroid carcinoma

Overview of undifferentiated thyroid cancer

Undifferentiated thyroid cancer is the most malignant type of thyroid cancer, with an incidence rate of about 10-15% of all thyroid cancers. Older and weaker people are more common, and the disease is rapid. Systemic metastases can occur at an early stage. It is generally considered that white thyroid cancer occurs more often. Benign tumor or low malignancy. Undifferentiated carcinoma (also known as anaplastic carcinoma or sarcomatoid carcinoma) is rare. It occurs more than 40 years of age. It is more common in women. It grows quickly and infiltration can occur early. And metastasis, high degree of malignancy, and poor prognosis.

Clinical manifestations of undifferentiated thyroid cancer

A long history of goiter, which has rapidly increased in the near future, and produces local compression symptoms, such as dyspnea, difficulty swallowing, jugular vein irritation, hoarseness and other symptoms, are due to tumor compression of the trachea, esophagus, jugular vein and laryngeal regurgitation Caused by the nerves. Pain in the neck, hard mass, fixation, and blurred borders.

Pathological changes of undifferentiated thyroid cancer

(1) Macroscopic view: large mass, irregular lesions, no capsule, extensive infiltration and destruction, gray section, often bleeding and necrosis. (2) Microscopically: cancer cells vary in size, morphology, and depth of staining, with many mitotic figures. Histologically, it can be divided into small cell type, spindle cell type, giant cell type and mixed cell type. Anti-Keratin, CEA and thyroglobulin antibodies can be used for immunohistochemical staining to confirm whether it is derived from thyroid gland epithelium.

Treatment of undifferentiated thyroid cancer

Surgery, radiotherapy, chemotherapy, and traditional Chinese medicine treatment. In 1983, Beichuan Xun isolated 20 (S) -ginsenoside-Rh2 from red ginseng for the first time. It has been confirmed that ginsenoside Rh2 has anti-cancer activity that induces apoptosis, differentiation and regulates the cell cycle of cancer cells, and enhances the body's natural immune ability to inhibit the proliferation and metastasis of cancer cells.