What is Cherubism?
Cherubism is a inherited childhood disease that affects the jaw. The condition results in loss of bone in jaws, which is quickly replaced by fibrous tissue. It includes the formation of bones of maxilla or upper jaw and jaw or lower jaw. Benign, fibrous tumors in the jaws cause the faces to enlarge, and swelling forces eyeballs to look slightly up. The condition that was first recognized in 1933 was awarded its name because plump faces and inverted eyes caused patients to look like cherubs of religious painting. The autosomal dominant genetic features have fifty chances of being handed over from their parents to their children. Tests show that the condition is usually caused by the Mutation of the SH3BP2 genes, which are located on the 4P chromosome, although some patients with disasseed that E has no mutation of this gene. In these cases, the cause is still unknown.
The disease usually manifests in children agedTwo and five years, when primary teeth begin to fall out, known as baby teeth. The diagnosis is usually based on physical overview, complete family history and diagnostic testing. Cherubism can sometimes be seen in X -ray, where it resembles giant cells of jaws such as fibrous dysplasia, other diseases that replace the bone with fibrous tumors. Computer tomography (CT) is a better diagnostic choice than X -ray for cherubism because CT is able to record soft tissue and display the range of lesions.
Most cases of cherubism are mild and correct spontaneously after puberty, when the fibrous tissue is gradually replaced by a new bone. In fact, most patients show no physical signs in adulthood. Fiber tumors are always benign and in most cases swelling is painless. Complications that may occur include malformated teeth, tooth loss and chronic lymph node inflammation. Sometimes the jaw movement is so limited from swelling that chewing is difficult.
severe cases of cherubism can lead to degradation or deterioration of the jaw and problems with vision, breathing, swallowing or speech. Treatment is not generally necessary in mild cases, but may be designed if there is pain, functionally limiting side effects or extreme distortion of features that cause psychological problems. The most common treatment includes surgically scratching excess fibrous tissue from bones. After using surgery, it was generally successful in reducing the progression of tumors and promoting bone regeneration. Liposuction was also chosen when the only reason for intervention was cosmetic.
If the child begins to show the properties of cherubism, it is proposed that it is transported to a pediatrician or a pediatric dental surgeon for evaluation. Although this condition is benign, it is important to eliminate other possible diseases. After diagnosis, doctors can help the patient to handle the condition until they eventually disappear.