What is Cushing's disease?
Cushing's disease is a rare condition that affects about 10 people out of one million caused by the excess cortisol in the body. Cortisol is most often known as a stress hormone because it is produced during the natural "fight or flight" of the body. It also reduces inflammation, helps the liver to remove toxins and helps the body to use salt properly. However, too much cortisol in the body can be dangerous for human health, causing problems such as reduced immunity and reduced bone mass. If it is not treated, Cushing's disease can lead to heart disease and possible death. The first is as a side effect of using glucocorticoid drugs such as asthma or other medicines that contain steroids. The second cause is excessive cortisol production in the adrenal glands. This second type of cushing is called Cushing's disease. Although it is also seen in dogs and horses, it is most common in humans.
Excessive cortisol production in the adrenal glands is the result of a small non -law tumor called adenoma, in the pituitary that J JThey are located near the bottom of the brain. The pituitary glands control adrenocorticotropic hormone (ACTH). ACTH is then transferred to the adrenal glands located near the kidneys. Based on the amount of ACTH, the adrenal glands of cortisol produce the body.
The most common symptom of Cushing's disease is weight gain, mainly in the trunk and around the face. Excessive fat deposits around the back of the neck, collar and face are often seen. Increased amounts of sweating, insomnia, hypertension and dry, thin skin is also common symptoms. Women can see an increase in hair growth and may suffer from irregular periods. High blood pressure, diabetes and longer Times healing can also be symptoms of Cushing's disease.
Cushing's disease is diagnosed by comparing cortisol levels in the urine of a person for 24 hours. In addition to urine test, magnetic resonance (MRI) and computational axial tomography (CAT) can also be used. JAkmile will be confirmed by Cushing's disease, surgery will be planned. During surgery, tumors in the pituitary will be removed. The radiation treatment can be used for a short time after surgery to ensure that the tumor does not reform. Steroid substitute medicines will also be used until the pituitary glands begin to function again.