What is graft disease versus host disease?
graft versus host disease (GVHD) is a health condition that can occur as a complication of bone marrow transplantation. The pulp contains stem cells that create blood cells in the body. Bone marrow transplantation can be carried out to treat certain types of cancer such as leukemia and lymphoma. Transplants help replace the bone marrow in the body of the patient who did not work properly due to the disease.
There are two types of transplants. One is carried out by harvesting stem cells from the patient's own bone marrow after a high dose chemotherapy killed cancer cells. The second type of bone marrow transplant includes the use of donor cells from another person who is transplanted to the patient. This type of transplant graft against the host disease may occur.
The aim of the bone marrow transplant is to enroll stem cells to the patient's immune system. This means that the donor's immune system replaces the patient's own immune system. When a slot versus hostite occursLinging disease, the immly system does not accept the patient's pulp and the body begins to attack itself.
It is not entirely understood why some people are found to be GVHD. The compatibility of donor pulp with the patient plays a big role in whether the patient develops complications after transplantation. Many cases of GVHD are mild, while others can cause serious problems and maybe being fatal.
When symptoms begin during the first 100 days after transplantation, it is known as acute GVHD. If symptoms start after this, the condition is called chronic GVHD. Symptoms of acute form of the disease include skin rash, stomach problems, including severe diarrhea and liver failure. Any organ in the body can be involved in the chronic GVHD. Symptoms often include dry eyes and skin, stomach cramps and hair loss.
The usual treatment of graft versus host diseases are steroids. Helppress Immune System andIt can cause the body to stop attacking. It is essential that the right dose is given to treat symptoms without completely killing a new bone marrow. Other medicines may be administered to treat pain and infections.
Some people with graft versus host disease respond rapidly to treatment. The prognosis depends partly on what organs are involved. Other factors affecting the outcome include the patient's age, the severity of symptoms and how soon the treatment began.
Although not all cases of graft disease and host disease can be prevented, there are some things that reduce the chances that the patient is developing. The closer the tissue match between the donor and the recipient, the lower the chance of developing the disease. Donors of siblings are often the closest agreement and if possible, they should be used.