What is a gram -negative sepsis?
Sepse is a health condition in which the whole body experiences inflammation because it seeks to fight an infection that has entered the bloodstream. Gram -negative sepsis is the result of a gram -negative bacterial infection. It is a potentially life -threatening condition that most often affects young children and older adults. Bacteria that do not respond to a stain called Crystal Violet are considered to be gram -negative. This lack of response to staining indicates the type of membrane that the organisms have. This causes an inflammatory response because the body cells respond to combat infection. Sepse occurs when these immune cells are exaggerated, causing an extensive body response.
Gram -negative sepsis causes a change in temperature when the body tries to compensate; and patients may have a fever or hypothermia. This can result in chills, increased heart rate and faster respiratory frequency. Laboratory changes show a high or low number of white blood cells, cells that help the body fight infection. Sepse can eventually startinfluence the function of organs, causing symptoms of mental confusion or impaired kidney function.
sepsis can lead to septic shock that often causes death. Since the symptoms of sepsis affect the organs, total blood pressure may drop, which requires other intravenous fluids to maintain perfusion. During a septic shock, the body does not have to respond to other fluids, resulting in the heart's inability to provide enough oxygenated blood into the tissues.
Gram-negative sepsis can be treated with antimicrobial therapy to help fight bacteria, causing inficeational. Early detection and treatment are important to reduce the risk of septic shock. Doctors often diagnose blood culture infection in which a blood sample to the growth of microorganisms is monitored in the laboratory. Blood cultures can take up to 72 hours to achieve the results so that antibiotic treatment can be started at a timewhen it is necessary to specifically identify a gram -negative organism. Some types of gram -negative bacteria that can cause infection and sepsis include Escherichia coli (E. coli), Klebsiella and Pseudomonas aeruginosa.
Above antimicrobial therapy and intravenous fluids may be necessary to treat gram -negative sepsis. Medicines to increase blood pressure are guaranteed if the patient does not respond to fluid increases. Some types of steroids can also be used to reduce inflammation. If the patient develops difficulty breathing due to reduced lung function, the use of the fan may be required. Combination of therapy therapy necessary to reduce harmful effects.
People who have certain conditions are at greater risk of developing gram -negative sepsis, including those who have a low level of immunity and people with traumatic injuries such as burns. Patients who used a large amount of broad -spectrum antibiotics to treat other infections may be prone to developing withPSE. In addition, age is a factor and sepsis more often affects children and very old.