What is hypophosphatemia?
hypophosphatemia or phosphate deficiency is a condition in which phosphate levels fall to a point that may be dangerous. Phosphate is a necessary mineral that requires many cellular processes, and hypophosphatemia can cause serious health problems. There are several mechanisms that may cause lack of phosphates, and several health conditions of which this lack is a feature.
phosphate is one of the most used minerals that the body requires. Most of the phosphate of the body is stored in the bones and is part of a mineral matrix that is excreted and maintained by bone cells. Phosphate is an essential part of DNA and other nucleic acids and is a key part of ATP, a molecule that is essential for almost all cellular processes that use energy.
The phosphate requirement for these key cellular functions means that an acute or chronic deficiency can have serious consequences. The most common cause of hypophosphatemia is increased phosphateing. This means that phosphate is excreted in a panelLech or urine instead of being used in the body. Increased phosphate excretion may be due to the range of metabolic deficiencies, many of which are inherited. In general, poor low -nutrient diet, such as vitamin D, which facilitates the absorption of phosphate cells, but may worsen the existing chronic phosphate deficit. Excessive use of certain types of antacids can cause hypophosphatemia, especially those containing aluminum, magnesium or calcium.
type of symptoms of hypophosphatemia, which may develop in a given individual, depends on the cause of phosphate deficiency and its duration. Most cases of mild or short -term deficiency do not cause any symptoms because the body is able to compensate for lack of phosphate in the short term. The most problematic symptom for people with chronic disease caused by a lack of phosphate is the waste of bones that causes bone pain, fragile bone and significantly increased RIZiko fracture.
children who are chronically insufficient in phosphate are also endangered by kidney disease and hyperparathyroidism. This condition is a dysfunction of parathyroid gland, which can cause symptoms such as fatigue, depression, pain and nausea. Children can also develop hypophosphatemic intersections that cause their legs to be seriously bowed. Most cases of lack of chronic pediatric phosphate are caused by hereditary metabolic disorder.
The treatment of chronic phosphate deficiency is administered on the basis of the cause of the deficiency. In situations where the problem is caused by reduced ability to absorb diet phosphate, such as a severe vitamin D deficiency, the basic cause is treated in addition to the provision of supplementary phosphate. People with metabolic disorders that reduce phosphate metabolism may usually have a problem with a high phosphate diet and vitamin D supplements.
Acute hypophosphatemia can cause a number of potentially dangerous symptoms. The lack of phosphates can causeCardiac symptoms including low blood pressure and increased risk of dangerous arrhythmia. Acute deficiency can also cause neurological symptoms such as confusion and other cognitive disorders, paralysis, seizures or coma. This type of phosphate deficiency is commonly treated with oral or intravenous preparations containing phosphate.