What is myoglobinuria?

myoglobinuria describes the condition in which a protein known as myoglobin is present in the urine. Myoglobin carries oxygen to skeletal and heart muscles to maintain its normal function. When muscle rabdomyolysis is destroyed, myoglobin is usually released in the bloodstream. It is then filtered by the kidneys and is excreted in the urine. Myoglobinuria usually occurs in trauma patients who have injuries and individuals who perform severe physical exercises. In children, viral infections such as influenza may lead to rabdomyolysis and myoglobinuria. Other conditions associated with myoglobinuria include lack of potassium, metabolic disease such as phosphophructokinase deficiency and hereditary muscle disease such as Mcardle's disease. Some food supplements, drug abuse and prescription drugs can also be involved in myoglobinuria.

Symptoms generally presented by patients suffering from rabdomyolysis are muscle pain and muscle weakness, which often leads to problems moving. Laboratory test for detectionCI myoglobinuria, called myoglobin urine, involves exploring the patient's urine sample. Urine color can be darker due to the presence of myoglobin. Once patients with trauma and patients with possible muscle injuries are evaluated to myoglobinuria, they are usually treated immediately to prevent complications.

One serious complication of myoglobinuria is acute kidney damage in which the patient suffers from a sudden reduction or loss of kidney function. This usually occurs when myoglobin is formed in kidney cells and causes obstruction or toxic damage to the area. Patients with acute kidney damage usually experience confusion, reduced urination, swelling at several points of part and bleeding. Other complications are hyperkalaemia, which is an increase in potassium in the blood, and hypocalcemia, which is a decrease in calcium levels in the blood.

Blood test called creatine kinase test (CK) can also be used to evaluate PAcines with muscle damage. Creatine kinase is also present in the brain, heart and skeletal muscles and its levels usually increase when muscle damage occurs. Patients who have been found to have myoglobin in the urine or increased blood levels in the blood are often accepted for treatment. Intravenous (IV) fluid is often administered for patient rehydration and sodium bicarbonate can be added so that alkalin urine can be added. Other medicines can also be administered to increase urination.