What is neuralgic amyotrophy?

amyotrophy is a descriptive term for muscle waste and neuralgia refers to nerve pain. In a specific condition called neuralgic amyotrophy, both of these symptoms in the area of ​​the arm and shoulders of the body experience. Paralysis is also a feature of this rare disease, but since the condition occurs in individual flares, symptoms are often excluded over time. Although some people have specific genes that cause the disease, other cases have no known cause since 2011. A typical patient suffering from the condition first experiences severe pain in one shoulder. The muscles of the affected area then became weaker and look wasting and the patient is unable to move the muscles. It seems that paralysis is caused by damage to the nerves that in healthy people give muscles to move. Nerves that send information about the feeling of a preschool may also be influenced by insensitivity or abnormal feelings such as tingling in the affected area.

The condition occurs in different episodes. People who have neuralgic amyotrophy due to genetics tend to have the first episode when they are between twenty and thirty years old, but some people are younger. Patients who produce neuralgic symptoms of amyotrophy later in life are more likely to form a form of disease for which scientists have not yet found a cause. Usually the episode hits quickly, but the patient may take years to improve. Over time and there are other episodes, the patient may suffer damage to the area and feel some chronic pain.

One possible explanation of the symptoms of the condition is that the problems cause the body's own immune system. This type of disease is called autoimmune diseases where the immune system molecules attack healthy cells inadvertively. It is possible that autoimmune reactions can specifically damage the nerves of shoulders and arms and therefore result in waste and paralysis and pain. This concept of the immune component of the state fromThe corticosteroids that interact with the immune system are one of the possible ways of alleviation, although there has been no effective treatment or treatment since 2011.

Some people were identified by a genetic cause. This is a mutation in a gene called September 9. In healthy people, it contains 9 instructions to create a molecule called septin-9. If a person has one or more copies of September 9 that creates a different form of septin-9, that person may develop neuralgic amyotrophy. The exact way in which the abnormal forms of septinum-9 cause the symptoms of the disease remains under the vestigination.