What is a neuroleptic malignant syndrome?
neuroleptic malignant syndrome (NMS) is a very serious disorder that generally develops in the use of neuroleptic drugs. These drugs are also called antipsychotics and often prescribe mental health conditions, which include elements of psychosis such as bipolar I and schizophrenia. Most neuroleptics, including drugs such as Zyprexa® and Giodon® (some of the latest developed), contain a warning regarding the potential of the development of neuroleptic malignant syndrome. The main symptoms of neuroleptic malignant syndrome are identified by a mnemonic fever, where each letter means the following: fever, encephalopathy, unstable vitals, increased enzymes and rigid muscles. According to the laymen, the most remarkable is extremely stiff muscles with a high fever. Blood pressure tends to be variable and high, patients may be deliial or unconscious, and blood work shows elevated levels of enzyme creatine phosphokinase (CPK).
naturally helps doctors most when they understand that the patient is on neuroLeptical drugs, especially if patients have just started taking a medicine. However, the condition, although rare, may develop in patients with certain drugs that treat the symptoms of Parkinson's disease, so neuroleptics are not the only cause of neuroleptic malignant syndrome. As already mentioned, most people who develop a condition are new to use a specific medicine, but sometimes NMS can develop when people have had certain medicines for a very long time.
When neuroleptic malignant syndrome is recognized and immediately treated, survival is very good. Unrecognizable condition and treatment may result in death, but statistics are currently unclear how often this happens. The mortality rate in some places up to 70%, but this must clearly relate to the untreated state, because the result is good for people who are hospitalized and immediately treated.
one of the significant challenges in the treatment of people with neuroleptThe malignant syndrome is those that newly prescribed antipsychotics may not indicate a condition, and if the drug does not work effectively, it may already have some delusions or psychotic symptoms. A person may not fully understand the nature of the drugs they use, especially in the early stages of treatment for serious psychiatric disease. This could indicate, especially for those suffering from psychotic symptoms that neuroleptics are best diagnosed in a hospital environment where patients can be monitored until they are mentally stable and are able to report dramatic changes in health.
If you had an NMS episode, it does not mean that you cannot take a neuroleptic again, even if you have to be carefully monitored and introduced to the new drugs slowly. There are concerns that those who had NMS can more likely to develop side effects on anesthesia. Anyone who previously had NMS should inform doctors and surgeons before the operation so that anesthesiologists can create the safest plan to continue the operation.