What is spinocelus metaplasia?
Squamalus metaplasia is a term used to describe cellular non -lawn changes in epithelial lining of certain organs such as bladder, uterus and lungs. Metaplasia occurs when constant stress or irritation causes a reversible maturation process that converts one differentiated type of epithelial cell to another. In the case of squamous metaplasia, different types of epithelial cells are converted or replaced by a spinocellular epithelium as an adaptation mechanism.
Cell type change may result in a reduced epithelial function. Once abnormal stimuli are removed, metaplastic cells return to their original form and function. Physiological stressors that are not removed in metaplastic areas can lead to dysplasia or precautionary changes. Dysplastic cells may develop into cancer neoplastic cells if the stressor or irritation is not removed over time. Column epithelial cells are an extended column shape that forms an endoc liningErvix, intestines and stomach. The column cell, whose cores are at a different height, is called a pseudostratified epithelial cell. Kabid epithelium is made of square cells commonly found in the exocrine gland and kidney tubules. The scenario epithelial cells are thin and flat, which in turn creates a smooth epithelium.
The cervix is a good example of a spinocelaous process of metaplasia and the resulting changes in neoplastic cells. The column epithelial cells are originally found in the endocervix, a cervical cavity. Estrogen and constant exposure to the acid vaginal pH pH are the triggers of the spinocelluous process of metaplasia involving the epithelium of the endocervix. In response to irritating pH, the fragile column epithelial cells begin to be replaced by a robust spinocestical type.
Squamalus metaplasia of endocervix also occurs as a result of merging with the neighboring area of EctoCervix. The intrusion of squamous cellsEctocervix begins to fulfill in endocervix areas and replaces the original column epithelial cells. Cancer neoplasia of cervix results in carcinogens, such as human papillomavirus (HPV), act as an irritating or stressor for metaplastic epithelial cells.
A similar metaplastic process takes place when chronic cigarette smoke irritates the pseudostratified epithelial lung lining. Cigarette smoke is a stressor that adapts pseudostratified cells to much stronger spinocellular cells. Even spinocellular cell types can undergo a squamous metaplastic change often observed in the bladder. Trigone bladder, or internal triangular area, place spinocellular epithelial cells that form the lining of the region. When adult spinocellic bladder cells are subjected to chronic inflammation, cells are subject to metaplastic change.