What is systemic vasculitis?
Systemic vasculitis is a serious health condition that adversely affects blood flow and blood vessel function. Systemic vasculitis, which often manifests itself in the presence of autoimmune disease, has the potential to cause necrosis or tissue death due to impaired oxygen flow. Treatment of this condition is focused on slowing its progression and generally involving administration of immuno-pressing drugs.
The beginning of systemic vasculitis, also known as systemic necrotizing vasculitis, usually occurs in the presence of autoimmune disease, such as polyarteritis nodosa or reumatoid arthritis, and may be considered a complication of pre -existing state. There is no known cause of the development of blood vessel inflammation that characterizes this rare condition. Systemic vasculitis is a progressive disorder that can affect the function of blood vessels anywhere in the body and ultimately endanger the health of tissues and organs.
Individuals who develop a systemic necrotizing vasculitisU, can experience a number of symptoms and symptoms that can affect several body systems. The initial onset of the disease is generally characterized by the presence of significant fatigue, fever and unintended weight loss. Some symptomatic individuals may develop skin lesions, rashes, ulcerated tissue or highlighted skin color affecting their limbs or numbers. In the end, tissues free of oxygen may begin to deteriorate, resulting in inflammation and discomfort in the affected area.
Systemic necrotizing vasculitis can also adversely affect human neurological function and cause impaired speech, movement and vision. Individuals can also develop chronic headaches, seizures or personality changes. Some may have pain, armor or weakness in their limbs and numerals. In some cases, joint discomfort may manifest itself, causing inflammation, convulsions and atrophy of the affectedMuscle tissues. Other symptoms associated with this form of vasculitis may include abdominal discomfort and bloody stools.
There are several tests that can be performed to confirm the diagnosis of systemic vasculitis. After physical examination and initial consultation, the individual may be transferred to a neurological examination that evaluates the functionality of cognitive, sensory and motor skills. To measure existing inflammation, the sedimentation speed test can be performed and blood tests can be used to assess the function of the liver and level of antibodies. Further testing may include a nervous biopsy, to evaluate any nerve damage that may exist, and urine analysis.
Treatment of systemic vasculitis is generally focused on slowing the disease progression. Corticosteroids such as prednisone may usually be administered to suppress the body's immuno-reaction to the presence of inflammation. Low -dose Applicesteroid treatment as part of the long -term treatment regimen often servesHowever, to reduce inflammation, it may expose an individual to a serious risk of side effects that may include fluid retention, threatened immunity and osteoporosis. Other anti -inflammatory drugs such as cyclophosphamide may also be used to treat serious symptoms of vasculitis; Although long -term use can cause side effects that include fatigue, discomfort of joints and reduced kidney function.
The prognosis associated with systemic vasculitis depends on the presentation of the disease, the severity of the symptoms and the overall health of the individual. Individuals with this form of vasculitis may have an increased risk of developing secondary infections that can spread to other parts of the body. Organs or tissues showing systemic necrosis induced by vasculitis can maintain permanent physical or functional deterioration.