What Is the Link Between Chemicals and Cancer?

Chemical carcinogen is a kind of chemical substance with tumor-inducing effect.

Chemical carcinogen

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Chemical carcinogens are

Commonly used chemical carcinogens include: polycyclic hydrocarbons (such as 3,4-

Carcinogenicity is screening

Chemical carcinogen vinyl chloride

Vinyl chloride is an important chemical raw material. It needs a large amount of vinyl chloride in the production of photo printing, product packaging, pharmaceutical packaging, household appliances and many other plastic products. However, only the vinyl chloride monomer is carcinogenic, and the plastic itself has no carcinogenic effect. Workers in vinyl chloride plants are 200 times more likely to develop liver cancer than the average person. It has been further discovered that vinyl chloride can also increase the incidence of cancer in the central slaughter system, respiratory system and lymphatic hematopoietic system. Animal experiments have also confirmed that tumors of the liver, brain, kidney, lung and lymphatic system can occur after inhalation of vinyl chloride.

Chemical carcinogens benzenes

As an organic solvent and chemical raw material, benzene is being widely used in industry. The production of chlorobenzene, nitrobenzene, perfume, drugs, pesticides, synthetic fibers, synthetic rubber, synthetic plastics (polystyrene), synthetic dyes, etc. uses benzene as the raw material. As a result, workers exposed to benzene are very common. People with long-term exposure to benzene can cause chronic benzene poisoning, which is manifested as a decrease in white blood cells and thrombocytopenia, which severely reduces whole blood cells, and can develop into aplastic anemia. Also, benzene can cause leukemia (blood cancer). The duration of leukemia caused by exposure to benzene varies, ranging from a minimum of 6 months to a maximum of 20 years, with an average of 2 to 3 years. It can also occur months to years after stopping or reducing benzene exposure.

Chemical carcinogen

Dichloromethyl ether is a very strong carcinogen, which can occur in rats after 10 inhalations. The tumor is usually found in the lungs and nose. Long-term exposure to diclofenac is also susceptible to lung cancer.

Chemical carcinogen polycyclic aromatic hydrocarbons

The earliest research in chemical carcinogens is polycyclic aromatic hydrocarbons, which are produced by the thermal decomposition of carbon-containing substances. Organic compounds can generate a lot of hydrocarbon-containing free radicals when they are not completely combusted. After complex post-polymerization processes at high temperatures, various polycyclic aromatic hydrocarbons are formed. Polycyclic aromatic hydrocarbons are mainly benzofluorene, benzoanthracene, dibenzoanthracene, dibenzofluorene, dibenzophenanthrene, methylcholanthrene, and dimethylbenzoacridine. Mainly from soot, coal tar, asphalt, mineral oil. Occupational workers exposed to these substances have an increased incidence of cancer, mainly lung cancer, skin cancer, laryngeal cancer, and gastric cancer. It has been found in animal experiments that benzoxanthene can induce liver cancer by oral administration and lung cancer by inhalation; benzopyrene skin smear can cause skin cancer.

Chemical carcinogen aromatic amine

Following PAHs, carcinogenicity of aromatic amines is an earlier and more deeply studied chemical substance in occupational tumors. Aromatic amine compounds are widely used in dye industry, rubber industry and pharmaceutical industry. Types of aromatic amines include 1-naphthylamine, 2-naphthylamine, benzidine, 4-aminobiphenyl, auramine, magenta, and the like. Aromatic amines mainly induce bladder cancer. Aromatic hydrocarbons can be carcinogenic after being absorbed into the body through the respiratory tract or skin. The main occupations that can be exposed to aromatic amines are the direct production of naphthylamine, benzidine, 4-aminobiphenyl, and aurylamine, Lu Hong and other chemical factory workers; workers who use naphthylamine and benzidine as raw materials to produce dyes, pigments and pesticides; Use of synthetic dyes as workers in the fiber printing and dyeing industry; hair dyers in barbershops; workers using aromatic amines as antioxidants in the production of rubber, cables, and wires; dimethylamine testing in biochemical and clinical laboratories; and supplies for germ cells Dye staff; staff using o-dimethylaniline for free chlorine inspection and bacteria room supplies red as dye. All of the above situations have problems with occupational exposure to aromatic amines.

Chemical carcinogen

Nitrosamine compounds can be divided into nitrosamines and nitrosamides. Nitrosamine compounds are used industrially as solvents and are also associated with industries such as rubber, dyes, lubricants, explosives, pesticides and the like. It is often synthesized in nature from secondary amines and nitrites under acidic conditions. Protein heat decomposition and food cooking may be the source of secondary amines in human diets. Under acidic conditions, secondary amines and nitrous acid combine to form nitrosamines. Therefore, such substances are often found in food, beverages and tobacco in the general population. Nitrosamine compounds are extremely potent carcinogens. Few animals do not develop cancer after being treated with nitrosamines. Nitrosamine compounds mainly cause esophageal cancer.

Chemical carcinogen pesticide

Many pesticides have carcinogenic effects. Pesticides are basically divided into three types: organic chlorine, organic phosphorus and organic nitrogen. Organochlorine mainly induces liver tumors, and organophosphorus can cause breast and ovarian and organic nitrogen. Organochlorine mainly induces liver tumors, organophosphorus can cause breast and ovarian tumors, and organic nitrogen is associated with lymphoma.