What is the most common pathophysiology of osteoporosis?
pathophysiology is a term that describes the changes that occur when normal biological processes become abnormal. Thus, the pathophysiology of osteoporosis refers to the changes that occur in the body due to osteoporosis. People with this condition suffer from a number of symptoms of bone density loss, often due to long -term lack of calcium.
Osteoporosis has only a few specific symptoms that can be recognized in people with diseases, one of which is more fragile bone. This situation results in significantly increased risk of bone fractures due to falls and other injuries. Fractures related to osteoporosis tend to occur in bones that would normally not be susceptible to damage by a simple fall. These include wrist bones, hips, ribs and bones in the vertebrate column. These factors are bone forming and bone resorption. Normal healthy bone is constantly repaired and rebuilt; Some estimates indicate that up to ten percent of bone tissue passes through this process ine healthy body.
bone formation is a process in which bone mass is deposited with cells called osteoblasts . Bone resorption is the opposite process: cells called osteoclasts absorb bone mass. These two processes must remain in perfect balance to maintain a healthy level of bone density. Some of them with osteoporosis, bone formation and bone resorption are unbalanced, causing the bone to become less dense, fragile and more prone to fracture.
Several different factors can lead to an imbalance between bone storage and resorption. One of the most common is to reduce estrogen levels that occur in menopause women. This reduction causes the bone resorption rate to increase bone formation.
Another common mechanism of pathophysiology of osteoporosis is the lack of calcium. Bone mass is constantly stored and partially reabsors to give the body a supply of calcium it needs forBasic tasks such as muscle contraction and neurotransMise. The reabsorbed bones release the calcium that enters the bloodstream and is distributed to the cells that require it. If the calcium is not provided by a diet, more minerals must be maintained from the bones and this process reduces the speed at which the bone mass is stored by osteoblasts. This deficiency may be impaired by a deficiency of vitamin D.
other organs, including thyroid and parathoroid glands, exclude hormones that can play a role in the pathophysiology of osteoporosis. The thyroid romance excludes a hormone called calcitonin, which increases the speed of storage of bones osteoblasts. The parathyroid glands secrete the hormones of the body position, which has many roles, including this speed at which the bone mass is reabsorbed. The imbalance in the levels of one of these two hormones may be important in the development of the pathophysiology of osteoporosis.