What is the ratio of renin-aldosterone?

Renin-aldosterone ratio is a value that is calculated after measurement of concentrations of renin and aldosterone in the blood. It is most often checked as part of the diagnostic assessment of high blood pressure, also known as hypertension. Both of these hormones are part of the Renin-Angiotensin (RAS) system that helps the body to maintain blood pressure. Checking the Renin-aldosterone ratio can provide information about whether renin or aldosterone levels are high compared to them. The high ratio most often indicates the narrowing of the arteries of kidney feeding, while the low ratio suggests that the tumor producing aldosterone is present.

To understand why the ratio of renin-aldosterone provides important information about possible pathological processes occurring in the patient, helps to understand what these hormones do and how they relate. Renin is a hormone that is made by the kidneys and is excreted in response to stimuli, such as low -blooded pressure or low blood flow through the renal system. Within races activates Renin Another hormone called angiotensin, which serves for many purposes. It can increase blood pressure through arterial vasoconstricting or narrowing of blood vessels that transmit blood from the heart to distant areas of the body. Angiotensin also helps to release aldosterone, another hormone that can increase blood pressure, from the adrenal glands.

Because Renin and Aldosterone are part of the interconnected system called RAS, which serves an important physiological purpose of maintaining sufficient blood pressure whenever one element of this system is too active, the affected patient may exert hypertension or high blood pressure. On the basis of the fact that the patient has increased blood pressure, it is difficult to determine whether one of these hormones is the main cause of this problem. Under the reasons, in selected patients who have a difficult to control blood pressure that is resistant to antihypertensive drugs, the Renin-aldost ratio isERON checked.

The high ratio of renin-aldosterone suggests that it produces too much renin through the body. This can rarely be caused by a specialized tumor that produces this hormone. However, renin levels increase more often because blood narrows into the kidney, which is the most common condition due to atherosclerosis. Renin is overproduced because only the low blood flow reaches the kidneys due to the narrowing of the arteries.

with a low ratio of renin-aldosterone indicates a problem with overproduction of aldosterone. Normally, the race is needed to release aldosterone from the adrenal glands. If there is a tumor in the adrenal gland, which produces aldosterone, it is a tumor, a condition called Conn Syndrome results, causing hypertension and problems with Lyte electronic. Aldosterone -producing tumors can often be removed by surgery, allowing the patient's high blood pressure to return to a normal range.