How effective are antibiotics for sepsis?

The effectiveness of antibiotics for sepsis depends on many factors. Treatment is most successful in healthy patients who receive rapid critical care and who do not develop septic shock. Inflammation and subsequent deprivation of oxygen are the main causes of organ damage during sepsis, and they adversely affect the success of the treatment of antibiotics. If the infection is caused by bacteria resistant to antibiotics, complications are more likely. Neonatal sepsis is particularly dangerous and requires a gentle balance of antimicrobial and other treatments to prevent death or brain.

sepsis occurs when a systemic bacterial infection causes the immune system to respond inflammation. It is treated with hospital care, which includes fluid support, antimicrobial and anti -inflammatory agents. Antibiotics are the basis of treatment from the fight against the spread of bacteria and the effects of their toxins are essential for the patient's survival. Successful use of antibiotics for Sepsis depends, among other things, on specific microorganism and on the strength of immune sysof the patient. If many tissues ignite, death may arise when blood clotting cuts off oxygen supplies and causes more organs disorders, a condition called septic shock.

Antibiotic efficacy for sepsis is the highest when patients are rapidly treated during infection and have no prolonged hypotension caused by septic shock. Early treatment reduces the patient's chance of shock due to immune response. This, in turn, reduces the risk of organ damage and gives antibiotics enough time to destroy or reduce bacterial blood. The total quality of hospital critical care is important in minimizing the effects of inflammation or toxins excreted by bacteria and affects the effectiveness of treatment. Patients who have a surgery of the heart valve valve tendency to have a high risk of complications if they become septic.

Infections obtained in the hospital are caused by bacteria that have been resistant to many norMally prescribed antibiotics. Even with early and appropriate drug selection, sepsis has higher mortality from resistant bacterial strains. For example, Staphylococcus Aureus is resistant to penicillin and similar drug class. Sometimes cephalosporin antibiotics are quite successful in the treatment of sepsis obtained in the hospital, but some microorganisms have become resistant to them. Aminoglycosides are effective in reducing the patient's death from resistant bacteria strains, but these drugs sometimes cause kidney damage.

Antibiotic treatment for neonatal sepsis is quite demanding. Neonatal sepsis has a mortality of up to 50% in untreated cases, sometimes due to inflammation around the brain due to bacterial meningitis. Intravenous use of antibiotics for neonatal sepsis is quite effective if this happens soon. The selection of antibiotics for sepsis of this species varies according to the bacterial type, the history of the mother and the degree of infection in a particular intensive care unit where the infant is treated.