What are the antagonists of aldosterone?

Aldosterone antagonists belong to the category of drugs that help treat heart disease and certain types of kidney disease by blocking the action of aldosterone, a steroid hormone that can cause high blood pressure and other serious problems related to the heart function. The human body produces aldosterone under normal conditions to maintain water and salt, but individuals with heart failure can have excessive amounts of aldosterone that cause potassium problems, overload, heart enlargement and scarring of blood vessels. Medicines that are classified as aldosterone antagonists have a link to aldosterone receptors in blood vessels and hearts to block the hormone. These drugs can sometimes be used in conjunction with other heart or kidneys. It is also used in some individuals who are heart failure of ISPlay after a coronary event. Aldosterone blockers can often rapidly reduce heart failure symptoms, including foot swelling and respiratory problems caused by surplusAdding body fluids. These drugs are usually administered together with a different type of diuretic or fluid reduction of the drug.

Patients with high blood pressure, diabetic nephropathy or heart failure are sometimes treated with ACE inhibitors or Angiotiss-II receptor blockers that suppress the levels of aldosterone in the individual's bloodstream. These drugs can often lead to a condition known as Aldosteron Escape, in which aldosterone levels gradually begin to return to the condition before treatment despite drugs. Aldosterone antagonists, which can be used in parallel with other drugs blocking aldosterones, are expected to reduce the occurrence of aldosterone leakage.

Aldosterone antagonists can sometimes cause hormone changes in women, leading to symptoms such as reduced voice or excessive hair growth. The drug category known as selective antagonists of the aldosterone receptor, orSaras has fewer side effects related to hormones. One of the significant risks of treatment of any variety of aldosterone blocker drugs is the development of hyperkalaemia, a dangerously high level of potassium in the blood. This condition can lead to heart arrhythmia or other severe heart disruption.

Individuals treated with aldosterone antagonists are recommended to avoid food -rich food food. These meals may include fruits or fruit juice, certain vegetables, wheat bran and some types of meat. Patients using these drugs should also avoid taking non -steroidal anti -inflammatory drugs or NSAIDs. COX-2 inhibitors are also contraindicated, as well as any medicine or supplement that has the potential to increase potassium levels.

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