What are different types of buprenorphin treatment?
Buprenorphine treatment is primarily administered as a sublingual tablet, injection or transdermal patch. Tablet and injection formulations are used for detoxification and long -term substitution therapy in patients depending on opioids. The transdermal patch is marked for the suffering chronic pain. Other forms of buprenorphin treatment can be administered using a sublingual film or implant. These types of buprenorphin treatment are for the treatment of opioid dependence. Drugs are administered in the doctor's office under careful supervision. The company responsible for the version of the sublingual buprenorphin tablet has also developed a sublingual film for drug management. The film is interchangeable with a tablet, although many patients prefer the taste of the film over the tablet. The film dissolves quickly and connects to the mucosa of the tongue, preventing patients to swallow or spit medicines. Naloxone is an antagonist who eventually discourages abuse or abuse of tablets as an injection by intravenous administration. Naloxone is not enough to reverse the effects of the rotSingle on opioids without buprenorphin. Based on the results of clinical trials in humans, patients dependent on opioids are recommended by a sublingual tablet and a film showing mild withdrawal symptoms.
Implantable formulation of buprenorphin uses a permanent release mechanism to treat opioid dependence. One of the benefits of administering drugs through the implant of the polymer matrix, unlike other administrative routes, is the reduced risk of non -compliance with the patient's dosing instructions. It also prevents the drug from diverting for non -medical use.
Thetransdermal patch containing buprenorphin treatment is a viable alternative to non -per -drugs used to treat chronic pain. The patch releases drugs slowly over a few days, up to 96 hours. This type of buprenorphin treatment is ideal for cancer patients who suffer from moderate to severe pain and grim patients who mAim a similar level of pain. Musculoskeletal and neuropathic pain can be treated with buprenorphin patches.
New types of buprenorphin treatment have occurred in an effort to improve the long -term therapeutic properties of treatment of opioid dependence and chronic pain. As regards the treatment of chronic pain, in some eastern countries the formulation of anesthesia administered directly into the spine such as India has been used. The reported advantage for the patient is up to 10 hours without pain after administration of the spine buprenorphin.
buprenorphine is a semi -synthetic opioid and an alternative to the methadone. Due to the drugcological action of buprenorphine, its analgesic effect is the result of partial agonistic activity at receptor sites that create a blockade effect as opposed to methadone. In principle, buprenorphine binds to receptors in the brain stronger than other opioids, which inhibits them from binding when buprenorphine is present.