What are the different types of stent coating?
stent coating is a surface material placed on a stent of a metal or polymer eye that is implanted in the body to open the previously blocked arteries, and the coating usually serves one of three purposes. Passive stent coatings are inert materials to prevent rejection of responses that can stimulate the accumulation of tissue on the stent itself, which is facilitated by blood circulation or cell growth into the stent holes from the endothelial wall. The endothelial wall is a thin layer of living cells or epithelium on the inside of the blood vessels, which tends to grow into holes in the stent and restore the blocking of the artery. The stents of eluting drugs also generally have two types of coatings, which are pharmacological substances designed to prevent restenosis or thrombosis as common side effects of stent implants.
the material of the stent that is designed to provide a padding that chemically or biologically neinIt erags with the body, moves from metals such as gold to naturally occurring plastic compounds such as phosphorylcholine. Gold is one of the first types of stent coating to be tested, and due to the inert nature of the metal in the human body, it has shown both antibacterial effects and natural ability to reduce thrombosis, coagulation of blood around the stent surface. However, gold coated stents have shown an increase in restenosis or repeated narrowing of the artery over time. Phosphorylcholine (PC) is chemically similar to the outer layer of red blood cells, so it also shows the ability to reduce thrombosis as a stent coating. One of the advantages with the PC stent coating was that it has shown minimal side effects for a six -month point for implantation, and this is attributed to the fact that the substance biologically mimics the outer wall of red blood cells.
other types of passive stentus material include heparin to reduce thrombosis, which can also be used in combination with coatings eliminating medicine and nanometer moviesSimilar diamond carbon (DLC), which has been shown to reduce cases of hyperplasia. Hyperplasia is an abnormal enlargement of the blood vessel due to cellular growth. Both silicon carbide and titanium nitride have also been tested as a form of passive stent coating. Silicia carbide can be linked to hydrogen, giving it the ability to reduce thrombosis and titanium-nitride oxide is used to shoot stainless steel stents to reduce both hyperplasia and platelet bindings to the wall wall.
stent coatings Eluting drugs are usually a cytostatic nature. This means that the drug suppresses the division of cells in the stent area instead of actually killing living cells, as cytotoxic drugs do. While stenting drugs are much more expensive than the types of inert stents, studies since 2010 have shown that they can reduce restenosis after nine months from 36.3% with untouched stents to 8.9% for drug -covered versions. Repeated procedures and heart attackY after the stent implantation, they were also significantly lower, at 8.8% in an average patient with a coating of an eluting drug compared to 21% for unloaded versions. Hirudin is one form of a natural drug studied as a coating of the stent, which is an anticoagulant compound obtained from the glands of the leech.