What factors affect sufficient dosing of benzodiazepine?

Many factors affect the dosing of benzodiazepine, including accompanying drugs, methods of administration and health of the patient. Doctors usually prescribe drugs based on individual needs, taking into account the specific requirements and condition of the patient. This group of drugs causes a soothing effect and benzodiazepine side effects include dizziness, sedations and lack of physical coordination. Benzodiazepines with other drugs that affect the central nervous system combine the effects of drugs that may require benzodiazepine dosing in patients who use antipsychotic or seizure drugs. Individuals should have caution when using benzodiazepines with antihistamines and barbiturates and should not combine benzodiazepines with alcohol.

Benzodiazepine dose varies depending on whether the patient receives drugs orally, intramuscular or intravenously (IV). The body does not absorb and circulates oral drugs as quickly as medicines that enter the bloodstream immediately through IV. BenzodiazepIny, which immediately do not close to the receptor sites, accumulate in oily tissues of the central nervous system and the rest of the body. Patients with lower body fat levels than usually may experience increase in side effects due to a larger amount of drugs circulating in the bloodstream. Lighter patients require lower benzodiazepine dosage than patients with a comparably size with more fat tissue.

Patients with kidney or liver disorders are not easily able to metabolize and eliminate drugs, which increases the blood levels of benzodiazepines. These patients have the therapeutic effects of lower benzodiazepine doses. Similarly, older people often show reduced ability to metabolize or eliminate medicines from the body. The effective dose of benzodiazepine in the older patient may be one third to half lower than in younger patients. Benzodiazepine side effects in elderly often include confusion or excess sedation.

Doctors usually prescribe benzodiazepines for anxiety or as a sedative on a intermittent or short -term basis, as drugs usually become customary. Sudden termination of the drug causes the withdrawal of benzodiazepine with symptoms that include abdominal cramps, behavioral disorders and convulsions. Patients may also have hallucinations, show psychotic behavior or have seizures. Depressed patients using benzodiazepines may exacerbate symptoms that include suicidal thoughts. Patients with symptoms of depression, anxiety, or panic disorders may require a reduction in abling surveillance doses.

individuals should only use benzodiazepines under the supervision of a doctor. Benzodiazepines are safe for suitably diagnosed patients who do not include the use of pregnant women or women who plan to conceive. Research shows that benzodiazepines can cause various congenital defects and death of unborn children. Breastfeeding planning should be equally careful.