What factors affect a sufficient dose of bisoprolol?

B1 Adrenergic receptors B1 or beta-blocker, bisoprolol, was approved in 1992 by the administration of food and drugs of the United States (FDA) for use in the treatment of high blood pressure. In 2011, it is used to treat a wide range of other conditions, including angina, fear in the stage, reduced blood flow to the head and to prevent post -traumatic stress disorders. Despite their relatively harmless safety profile, some side effects of bisoprolol may be serious, including exacerbation or precipitation of low blood sugar, asthma and bradycardia. People endangered by these conditions, as well as people with liver or kidney disease or who take certain medicines, should take a lower initial dose of bisoprolol. As a result of genetic resistance to beta-blockers, diuretic dose together with black patients who use drugs such as bisoprolol should be an active dose.

using this beta-blocker to treat high blood pressure in adults younger years65, initial dose of BISoprolol 5 mg should be administered orally once a day. A maintenance dose between 5 mg and 20 mg can be administered once a day if necessary. The same regime without a maintenance dose can be used to prevent angina attacks, to treat premature ventricular depolarization, or to control supraventricular tachycardia. Depending on the patient's reaction, bisoprolol dose may be increased to 10 mg after three days and then to 20 mg for the next three days.

In adult patients with congestive heart failure, the initial dose of 1.25 mg should be used orally once a day, with or without food. If this dose is well tolerated after 48 hours, it can be increased by 1.25 mg. The evaluation of the increase in the dose should be carried out every seven days, and the increase does not exceed the daily dose of bisoprolol 5 mg.

Recommendation for dosage for patients with medium -sized sufficiency of kidneys - defined as HLADiny CRCL less than 40 ml/min - an initial dose of 2.5 mg once daily should be administered, with a dose of maintenance between 2.5 mg and 20 mg once daily. Patients suffering from reduced liver function should follow the same dosage recommendations. Caution should also be used in determining the appropriate dose of bisoprolol, so that patients with a history of asthma, bronchospastic disease, heart failure, peripheral vascular disease or diabetes give more than 20 mg per day.

interruption of this drug should be carried out gradually and under close medical supervision. After sudden ending of treatment, there were several examples of exacerbation of angina and sudden heart attacks and ventricular arrhythmias. These risks are even more pronounced in patients with coronary arteries.