What factors affect sufficient dose of duloxetin?

Duloxetine is a selective drug of inhibitor reuptake of serotonin (SSRI) used to treat depression, generalized anxiety disorders, fibromyalgia, diabetic peripheral neuropathy, chronic musculoskeletal pain and bladder syndrome. In some countries it is only available with a doctor. The therapeutic dose of duloxetin usually ranges from 40 to 120 milligrams (mg) a total per day, with a full amount of two daily or once a day to be collected throughout the amount. Sufficient dose of duloxetin is one that adequately treats the patient's symptoms and avoids - if possible - most of the side effects. The specific amount of dosage that reaches both ends depends on the diagnosis of the patient, weight, age, gender, lifestyle, medical history and contemporary drug regime. For the treatment of depression, the drug is usually originally used twice a total of 40 mg. The dose may be increased depending on the depressive symptoms and side effects when present. In the treatment of anxiety, fibromyalgia, chronic muscle pain, or diabetic peripheral neuropathy, an initial dose for adults usually 60 mg daily. The dose of duloxetin greater than 120 mg per day is unusual and is not recommended.

The weight, age and sex of the patient is also considered to determine the appropriate dose of this drug. The general rule is that patients with underweight should start at a lower dose of duloxetin than overweight or obese patients. Administration of this medicine also requires seniors that the lowest possible dose be used to achieve therapeutic effects, since this population often has a higher incidence of problematic side effects. The patient's lifestyle - working or retired, active or sedentary - can determine whether a side effect, such as low blood pressure, dizziness or blurred vision, is incapable or only uncomfortable.

in determining sufficient dose of duloxetin should beT also taken into account the patient's medical history and the current regimen of the drug. The history of alcohol abuse, hypertension, liver or kidney disease may require lower doses of duloxetine or even the consideration of an alternative drug. The opening of duloxetin within two weeks of using monoamine oxidase inhibitors (Mao) such as isocarboxazide, phenelzin, seagillin or traylcypromin is contraindicated. In addition, patients should not start duloxetine if they currently take linezolid, lithium, tryptophan, tramadol, sumatriptan, zolmitriptan or risatriptan to avoid life -threatening interactions. Even conventional medicines, supplements or compounds such as wort, acetaminophene and caffeine sv.