What is the toxicity of aminoglycoside?
aminoglycosides are a set of antibiotics in normal use. Although individual drugs are beneficial in certain situations, the class as a whole carries a set of side effects that can be potentially dangerous; The term of these serious side effects is the "toxicity of aminoglycoside". Patient function and hearing can be affected by medication and the resulting damage can be permanent. Antibiotics
are drugs that can kill bacteria and are useful treatment of bacterial infections. Individual antibiotics may be related to the structure and method of effect and scientists place these drugs in classes. Aminoglycosides are one such group and include medicines such as gentamicin, neomycin and kanamycin. Since each drug in the group has similar mechanisms of effect, they tend to have the same side effects in the body.
In general, any medical problem that arises as a result of the use of the drug is called a side effect. When a side effect involves serious damage to the organization, then can be side effectEC referred to as a toxic effect. The toxicity of aminoglycoside usually affects either the kidneys or ears, and the effects on the ears are more likely to be permanent than the effects on the kidneys.
When the kidneys are adversely affected by the treatment of aminoglycoside, the body does not remove enough waste products from the blood. Up to 10% of people using aminoglycoside develop kidney problems; This occurs higher doses, long treatment and growing age of the patient. Ear damage, which is technically known as ototoxicity, occurs in approximately the same percentage of people and has the same risk factors.
Some genetic mutations may expose a person to a greater risk than others for the development of the form of damage to aminoglycoside toxicity. Acceptance of other antibiotics, such as vancomycin, amphotericin B and cycling also increases the risk of aminoglycoside toxicity and people who already have kidney disease are more sensitive. RiSigism is also higher if the patient previously used aminoglycoside drugs.
Medical treatment may reverse kidney damage in some people, but the benefits are less achievable by ototoxicity. The toxicity of aminoglycoside is therefore an important side effect on aminoglycoside drugs. In addition, antibiotics in this group can also worsen people with muscle conditions such as myasthenia gravis , and may slow recovery from anesthetics such as successionlcholin or curare. In deciding which treatment, the physician must provide these risks against the potential risk of impairment of infection.