What is the connection between neutropenic and chemotherapy?

The connection between neutropenic and chemotherapy is that chemotherapy can cause neutropenia. Neutropenia is a blood disorder that is characterized by an unusually low number of neutrophils. The main component of the congenital immune system is neutrophils of the main defense against blood bacteria and prevents infection. Chemotherapy is used as treatment of cancer, autoimmune diseases and inflammatory diseases and applies drugs that are selectively toxic to a particular microorganism, virus or bacteria.

neutropenia is a common side effect of chemotherapy and about half of the patients who have undergone this treatment are experiencing a connection between neutropenic and chemotherapy. Chemotherapeutic agents attack fast dividing cells such as cancer cells and interfere with DNA production. This also affects normal cells such as neutrophils. Chemotherapy reduces the number of neutrophils that are produced by bone marrow, resulting in chemotherapy induced neutropenia (CIN).

during chemotherapy with neutrOutline usually begins to reduce about one week in each round of treatment and reach the lowest point about seven to 14 days after the wheel is completed. Usually bone marrow will restore normal neutrophil production and levels will increase, which will reach normal levels after three to four weeks. Once the normal level is reached, additional wheels of chemotherapy can be given. The immune system is suppressed, so antibiotics are usually given to the patient during this period.

CIN is an example of a connection between neutropenic and chemotherapy, resulting in chemotherapy reduces the number of neutrophils below the accepted normal lower limit of 2,500 per microliter - or 1,500 to microitery between blacks and people from the Middle East. The absolute number of neutrophils 1,000-1 500 per microlitry is classified as mild neutropenia, 500-1000 is medium and below 500 is severe. This subsequently leaves a patient with an increased risk of bacterial infection that maydependence on severity threatening life.

Symptoms CIN include fever, chills, sepsis, mouth ulcers and sore throat. Other symptoms include diarrhea and redness and/or painful swelling around the wound places. Infections often occur from bacteria that are already present on the skin and intestines such as Staphylococcus, which under normal immune conditions do not cause infection. CIN is diagnosed with a complete blood number, which includes the differential number of white blood cells and identifies the percentage of neutrophils present. Sometimes bone marrow biopsy will be performed to determine the specific cause.

CIN treatment may include antibiotic or antifungal drugs that help fight infection. The stimulating colony factor of granulocytes (G-CSF) can also be used to support neutrophils of prof.duction in the bone marrow. Corticosteroids, granulocyte transfusions and intravenous immunoglobulin therapy may also be administered when the patient is experiencing a connection between neutropenic and chemotherapy.

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prevention of infection is also crucial. Patients undergo chemotherapy are recommended to use strict hand washing to avoid large crowds or contact with infected people and avoid certain foods that increase the risk of food transmitted, such as raw vegetables, soft cheeses and insufficiently cooked meat. In serious cases, hospitalization in the insulating room and the use of gloves, dresses and masks for any contact may be forced.