What is the connection between simvastatin and diabetes?

Scientific research shows the connection between patients taking high doses of simvastatin and diabetes. The highest doses of this drug reducing cholesterol help prevent heart and strokes in high -risk patients. However, it has been shown that strong doses of simvastatin slightly increase the risk of diabetes 2. Since simvastatin is effective in reducing cardiovascular events, patients should not stop taking this medicine before consulting their doctors. Simvastatin is launched under the ZOCOR® brand in the United States. It slows the production of cholesterol body, thus preventing it from building on the walls of the artery. The accumulation of cholesterol can block blood flow to the body parts, including the heart and the brain. By helping this drug to reduce the amount of cholesterol and oily substances in the blood, it reduces the risk of stroke and heart attacks. Simobjects can also reduce the need for remedial surgery in people with a high risk of experiencing cardiovascular events. Patients with high doses occurred SnImplementing the risk of a heart event by approximately 16 percent. The strongest doses of drugs slightly increase the risk of patient diabetes 2. Type by about 12 percent compared to placebo. Type 2 diabetes affects only more than 25 million people in the United States.

According to this research, there was another case of diabetes 2. Type for every 498 patients who took a high dose of simvastatin for 12 months or more. Approximately three patients out of 498 were spared the main cardiovascular events. A total of approximately 8.4 percent of patients in clinical trials developed, although some were taking a slight dose of drug. None of the patients developed diabetes before studying.

There is no definitive explanation of this link between simvastatin and diabetes. Many factors that contribute to cardiovascular disease and need to use simvastatin also contribute to diabetes 2. It is possible that those individuals about treatmentThe high -dose simvastatin was prone to the development of the disease. There have been some speculation that diabetes could be caused by a sedentary lifestyle resulting from the pain of the muscle caused by simvastatin. The type of statin does not affect the risk of diabetes, only dosing.

Despite this connection between simvastatin and diabetes, the advantage of using the drug to prevent cardiovascular events prevails over the risk of disease development for most patients. Patients and doctors should discuss the possibility of developing diabetes in determining the appropriate simvastatinusage and the necessary lifestyle changes. Patients currently taking Simvastatin should not suddenly stop their regime without consulting their healthcare providers.

This medicine is taken once or three times a day in the form of a tablet. Patients usually begin with a low dose that gradually increases until the most effective level is achieved for individuals. Simvastatin is most effective as part of a lifestyle change that ranNaje low-cholesterol, low-fat diet and increased exercise. Common side effects are primarily gastrointestinal constipation and nausea. People with liver disease should not take simvastatin.

In addition to the link between simvastatin and diabetes, the United States United States and Healing Administration has announced healthcare workers that the highest doses of this statin can also cause myopathy. Individuals taking 80 milligrams per day are exposed to increased risk of muscle damage, especially during the first year of treatment. Factors that include the level of risk of risk to myopathy related to simvastatin and interaction with other drugs. Some forms of myopathy, including rhabdmyolysis, may cause serious organ failure. The dose of 80 milligrams was reserved in the United States only for patients who have taken it for more than a year without signs of myopathy.