What Is the Difference Between ARBs and ACE Inhibitors?

Angiotensin II receptor blocker (ARB) is a drug that can block angiotensin II receptor more effectively than ACE inhibitors in blocking vasoconstriction and water and sodium retention. And cell proliferation.

Angiotensin II receptor blocker

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Angiotensin II receptor blocker (ARB) is a drug that can block angiotensin II receptor more effectively than ACE inhibitors in blocking vasoconstriction and water and sodium retention. And cell proliferation.

The indication is the same as that of ACE inhibitor (ACEI), but it does not cause cough response. When patients are contraindicated in using ACEI drugs, ARB drugs can be used instead. Angiotensin II receptor blockers have a smooth blood pressure lowering effect and can be used in combination with most antihypertensive drugs (including ACE inhibitors). There are two types of angiotensin II receptors, namely AT1 receptor and AT2 receptor. Currently found that AngII receptor blockers are mainly AT1 receptor blockers. AT1 receptor blockers have a good antihypertensive effect without the adverse effects of angioedema, cough, etc. that convert enzyme inhibitors.

Including losartan, valsartan, irbesartan, candesartan, and telmisartan. Among them, candesartan has a strong effect, a small application dose, a long maintenance time, and a high peak, which is the best of these drugs at present.

Adverse reactions:

This product is well tolerated, with minor and transient adverse reactions, but dizziness symptoms have been reported in 1%, and orthostatic hypotension symptoms have been reported in less than 1%.