What is the relationship between corticosteroids and infections?
corticosteroids are a class of drugs that are often used to treat diseases that cause inflammation such as asthma, some allergies and rheumatoid arthritis. One of the side effects of corticosteroids is that drugs also suppress the body's immune system, which can facilitate infection. Although studies have shown that there is a connection between corticosteroids and infection, not every patient taking medication develops infection. Doctors usually advise patients that an increased chance of infection is one of the risks of corticosteroids.
Human adrenal glands are found on the kidneys. Adrenal glands work with the pituitary gland and the brain -called hypothalamus area to produce certain hormones. Two of these hormones, hydrocortisone and corticosterone, play a role in suppressing inflammation in the body and regulating the immune system. Corticosteroid drugs mimic the effects of these hormones. The boost of hormones in the body can be better suppressed by inflammation.
The relationship between corticosteroids and infections exists no matter what JAK patient receives a medicine. For some conditions, the best method of delivery is a pill or a liquid form that the patient uses orally. Corticosteroids may be injected or the patient may be given an ointment to be applied to the skin. Patients with asthma or allergies can receive an inhaler or nasal spray. The doctor decides which method is best for the patient's specific condition.
Although it is clear that there is a connection between corticosteroids and infections, the drug cannot be accused in all cases. Many of the conditions for which drugs are prescribed also endanger the risk of infection. For example, patients with chronic obstructive pulmonary disease (COPD) are at greater risk of pneumonia, although not to get corticosteroids than those without COPD. Although inhalation corticosteroids can work well to alleviate COPD symptoms, these drugs increase the risks of pneumonia development.
patientsshould discuss the potential risks and benefits of any medicine with their doctors before starting a new medicine. It is also important that the patient tells his doctor about any other drugs he takes. Despite the connection between corticosteroids and infections, corticosteroids may be the best choice for the patient's condition. The decision is best made by an informed patient and a physician who knows the patient's medical history.