What is the coagulation path?
The purpose of the coagulation paths of the blood vessels in the body is to give the body the opportunity and means to repair after injury. After piercing, these tracks of blood vessels can seal blood loss and provide surface wounds of anti -inflammatory assistance in exposure to viruses, bacteria and mushrooms that could penetrate the wound. There are two main coagulation pathways known as internal and outer roads. Normal functioning in these paths helps maintain a healthy balance of coagulation growth factors in the body organs. Bleeding triggers platelet plates, factors, fibrin and proteins that form a protective barrier known as a clot in sequential activations.
The inner coagulation path, sometimes called the track activation, is triggered by a meeting with a foreign substance such as plaque in the blood. This creates an inflammatory reaction and forms collagen. Collagen activates other blood and collision -known as a factor X, causing the inner path to converge with the outer coagulation path. The outer coagulation path is aboutBesby, when the tissue from the outer layers of the skin comes into contact with the blood through the turning point in the blood vessel. Tissue factors, along with other clotting in the blood, begin to bind to blood plates applied to the event and together form a half clot from a substance known as fibrin, which becomes a hardened clot.
The precipitation of drugs known as procoagulants mimics the clotting of paths that help the body to clot if necessary. Drugs that fight the body's ability to clot when the body is too easily clotting is called anticoagulants. The use of procoagulants and anticoagulants treats disorders when they occur in external and internal roads. Procoagulants are used to treat excessive, for example, deep wounds from deep punctures and thrombin and fibrin from roads are combined to form adhesive patch, which is sometimes used to seal blood vessels called aneurysm.
Imports occur from disorders in the coagulation path. Some of these diseases are diseases in patients with insufficient clotting, as in haemophilia and bleeding. Patients with too much clotting often suffer from various forms of thrombosis. Thrombosis, when the body collides too well, forms traveling clots that are stored in the circulation of the lungs, brain and heart and can cause death.
Secondary diseases can also be based on disorders of the normal function of the coagulation pathway such as lupus and some forms of cancer. Liver failure may occur due to insufficient ability to coagulate in the liver. SEPSE patients have a fibrinolysis disorder found in the coagulation path, which can lead to the condition of the well -known Yako -Seminated intravascular coagulation (DIC), as a result of very dangerous procoagulation imbalances.