What is Homeostase cholesterol?
Homeostasis cholesterol is any mechanism that contributes to the process of maintaining a balanced inner state of cholesterol in the living organism. Cholesterol, a necessary biological molecule in the human body system, performs various physiological functions, such as the action as a precursor for the production of bile acids, vitamin D and steroid hormones. It also works as a critical structural element in the cell membrane of each cell present in the body. Despite the beneficial and necessary cholesterol functions, disturbance in cholesterol homeostasis can cause increased risk of heart disease and disturbance of other home -ostatic feedback systems associated with cholesterol metabolism. One of the most basic system dysfunction of cholesterol imbalances can be seen in the cell membrane, because the ratio of polar lipid to cholesterol affects protein mobility and permeability of the membrane itself.
Like all lipids found in the human body, cholesterol is insoluble in the fluid part of the blood or in the bloodplasma, so the proteins must be transported. In the case of cholesterol, proteins known as lipoproteins "set" cholesterol particles for transport. The two most famous carriers are low -density lipoproteins (LDL) and high -density lipoproteins (HDL), as the numbers specified in laboratories that perform tests on cholesterol homeostasis. The total cholesterol balance can be attributed to three other proteins: chylomicrons, lipoproteins with very low density (VLDL) and lipoproteins of intermediate density (IDLS). One of the main causes of the primary homeostatic imbalance that can lead to the disease is the condition of these proteins disproportionate.
The most visible body that controls the homeostasis of the cholesterolulators system, but is a potentially harmful, free floating cholesterol from the bloodstream. HDLs are beneficial in maintaining homeostasis of cholesterol because they pick up and give potentially dangerous cholesterol directly back to the liver where it issynthesized into harmless bile acids used by the digestive system. LDL works less beneficial because they tend to store cholesterol in body cells and arterial walls. These are excessive LDL levels that have been shown to increase the risk of cardiovascular diseases.
In a healthy adult cholesterol homeostasis, it is firmly regulated by complex feedback loops. In this case, if a healthy patient eats a large amount of diet cholesterol, biosynthesis in the liver is significantly reduced to maintain balance. In an adult who has a high basic level of LDL, whether from poor eating habits or other genetic or health conditions, the feedback loop and systemic management can be amazed by the same abundant, causing dangerous homeostatic imbalance. In these cases, the use of drugs such as statin medicines, help the body return to a healthy cholesterol balance.