What is a contig?

Contig, an abbreviation for adjacent, either a segment of deoxyribonucleic acid (DNA) or on a product of overlapping segments that form a continuous, large, uninterrupted DNA sequence. By studying the maps of these segments, it is possible to discover the order of segments containing different sequences and contigyes can be added, removed or regrouted to form new sequences. CONTIG and library mapping enable scientists to identify alignment that could cause disease, provide a better understanding of how cells react under certain conditions, and allow the ability to clone favorable properties in living organisms.

genomic contigys are associated with one other overlap of corresponding sequence branded sets or corresponding sequence marks. Understanding this process of the building block used by the bases of the segments can be replicated or cloned into desired sequences, adding or eliminating less favorable segments. Scientists see these sequencejako maps onHighly detailed, computer programs DNA. The program provides visual distribution of bases used to design segments and segments used to create specific sequences. Using different color schemes, various Contig programs show this information as low, medium and high quality sequences.

Contig mapping often casts light on the causes of genetic disorders. For example, Williams syndrome creates symptoms of multi -system in children, including cardiovascular problems, elevated calcium levels in the blood and inability to prosper. Scientists have discovered a deletion of a zone affecting certain genes that may be caused by inappropriate overlap of contig. Another genetic childhood disorder, Cri-Du-Chat syndrome, also causes several symptoms, each of which each scientists believe to correlate with deletion and abnormal location.

also the analyery of the contig sequence in plant species. Every substituteHe sews unique for this plant and by obtaining maps of individual plant species scientists discover similar and variable properties that can contribute to health or deterioration of a specific type of plant. By analyzing contigys of segments and sequences in organisms carrying diseases, doctors can determine features that can then be used in the development of treatment. Mapping provides visual insight into possible genetic manipulations through sequential deletions or cloning.

Scientists can grow cloned DNA samples in bacterial artificial chromosome, yeast artificial chromosome or in P1, or phage artificial chromosome medium. These chromosomes contain anywhere from 50 to hundreds of thousands of bases that compile contigible segments. After the colonization period, the samples are extracted by means of a syringe and placed in a sequential gel of DNA, which is subject to electrophoresis and drying. Authoradiograph of readers and fingerprints of sequences. Scientists then scan the fingering finger into a picture withoubor, which can later be loaded into the Contig program.