What Is Agglutination?
Agglutination
- Word : agglutination
- Pinyin : níng jí
- Phonetic :
- English : agglutinate [1]
- 1. Refers to agglomeration; coagulation.
- Agglutinin
- Agglutination
- Hemagglutination reaction means that when the human body encounters some abnormal blood, the serum agglutinin in one blood will cause the corresponding agglutinogen on the surface of blood cells in the other blood to occur.
- When granular structures such as red blood cells and bacteria coexist with substances that can bind to their surface, the latter aggregates the granular structures together through the former's bridge action, which is called agglutination.
- Agglutination
- As agglutinating substances, there are: antibodies that are relatively anti-particle surface antigens, cytolectins that bind to red blood cell membrane substances, and various viruses. For example, because the antibody has a plurality of binding sites and the antigenic determinants on adjacent particles are combined with each other, the particles are aggregated into large agglomerates, and the agglutination can be detected with the naked eye. Agglutination reactions are widely used in blood group identification, antibody valency determination, and viral force determination.
- Agglutinin
- human's
- A, B, O blood group agglutinogens are glycoproteins. The protein part is the antigenic substance that determines the blood type. It is a polypeptide composed of 11 amino acids, of which threonine is the most abundant, and others include serine and proline. The polysaccharide portion is a mucopolysaccharide, including D-galactose, L-fucose, N-acetyl-D-glucosamine, N-acetyl-D-aminogalactose, and the like. The polysaccharide fraction determines blood group specificity [2] .