What is the genome annotation?
The
genome annotation refers to the genome section with information about the genetic data it contains. This is part of the process of genome projects, where the goal is not only the DNA sequence of the target organism, but also to understand what it does and how it works. Scientists can perform annotation in their laboratories and can share data with other scientists to associate resources and information. Online databases open to the public are available and some also allow the public members to submit their own annotations. It takes a long time sequencing the whole genome and it is common for scientists to initiate annotation before the genome decoding. With a part of the sequential DNA in the hand, the researcher can begin to annotate. Scientists may notice where genes appear to begin and stop, pay attention to distinctive DNA chains that contain the information function.
Computers are able to perform a certain annotation of the genome themselves. They can look for familiar patterns such as amino acid chains that appear at the beginning and end of genes. In an automated annotationThe computer can add notes to different parts of the DNA chain to provide information about it. It is also possible to compare segments from various organisms and look for dispersion that could provide important information about the species as a whole.
Genome manual annotation involves physical control of DNA. Many scientists use computers to display information and label, allowing them to enter how they work in the databases. In some cases, after automated annotation, manual check may be necessary to ensure that the computer has information about the correct condition. It can be a careful process and there are errors, which is one of the reasons for repeating packages of packages. If the annotation does not correspond to others in the same part of the DNA, people can evaluate information to determine what happened and fix the error.
It is not always possible to determine what the gene is doing during the genome annotation process. Scientists can mark genes and separate them from other componentsgenome, such as non -coding DNA, such as repetition. This information can be used in research because people develop theories about different genome segments. They can add to annotations to notice the function of the gene.