What Are the Symptoms of a Vitamin D Overdose?

Vitamin D excess is often an iatrogenic disease. Taking vitamin D in large quantities for a long time, especially using large doses to treat non-vitamin D deficiency diseases such as psoriasis, lupus vulgaris, and rheumatoid arthritis.

Hypervitaminia D

Overview of Vitamin D

Vitamin D excess is often an iatrogenic disease. Taking vitamin D in large quantities for a long time, especially using large doses to treat non-vitamin D deficiency diseases such as psoriasis, lupus vulgaris, and rheumatoid arthritis.

Symptoms of excessive vitamin D

The main symptoms are fatigue, headache, loss of appetite, thirst and urination, weight loss, nausea and vomiting, abdominal pain, constipation, decreased muscle tone, tachycardia and arrhythmia, itchy skin and acne-like manifestations. Soft tissue, large blood vessels, heart, lung, kidney tissue calcification and tissue destruction, skin metastatic calcium deposits are mostly located near the extremities and joints. Stones or calcification in the kidney can cause impaired renal function or uremia. In severe cases, fever, coma and even death may occur. Fibrous osteitis of the bone.

Vitamin D Examination and Diagnosis

Laboratory examination showed increased urine calcium, serum calcium levels above 2.88mmol / L, serum phosphorus above 1.29-1.62mmol / L, and ECG showed shortened QT interval and arrhythmia. X-ray examination of bone fibrous osteitis.

Vitamin D Treatment

Those with allergic or excessive vitamin D should discontinue vitamin D, low calcium diet, use furanilic acid diuretics, drink plenty of water, increase calcium excretion; when serum calcium is above 3.75mmol / L, corticosteroids, intravenous drip isotonic Sodium sulfate solution (not to be used for uremia), diuretics should be discontinued after serum calcium returns to normal levels, and corticosteroids should be gradually reduced and discontinued.