What Are the Symptoms of Jet Lag?

Jet lag syndrome is a symptom of fatigue, confusion, and poor sleep that many people experience after flying across time zones. The results of the study were published in the journal Nature Neuroscience. Scientists studied two groups of stewardess who shuttled in different time zones. The time required to overcome jet lag syndrome was different. Through research using advanced equipment such as magnetic resonance imaging, scientists have found that the right time lobe is also smaller in the brains of people who fly more frequently across time zones. The right time lobe is the part of the brain responsible for memory and cognitive abilities.

All life on earth has a physiological mechanism called

In the past, the conventional jet lag syndrome treatment method was psychological treatment instead of drug treatment. High-brightness light therapy is a popular method for the treatment of seasonal insomnia in the 21st century. In addition, vitamin B12 and benzodiazepines [such as Shule Anding ] The use of hypnotic drugs, but none of the above-mentioned treatments have brought expected therapeutic effects. However, compared with barbiturates and non-barbiturates, benzodiazepines [such as sulbutamidine] hypnotics do not cause drug resistance or dependence, and have higher safety. However, benzodiazepine hypnotics are well known and can produce some adverse reactions such as

As a new compound to regulate circadian rhythm. Melatonin is mainly composed of

Obviously, endogenous melatonin is an important factor for the regulation of circadian rhythm, but there are still doubts to be solved in order to achieve the expected drug treatment effect of melatonin. So people think that if the action of normalizing circadian rhythm can be established through natural products, it will be very valuable to use it to treat jet lag syndrome and some diseases caused by it. If this natural substance can enhance the biological activity of endogenous melatonin, or the safety and effectiveness of exogenous melatonin, its value will be extremely high.

Astaxanthin is a red carrot pigment. It is found in ornamental fish, salmon, shrimp and other bodies. It is also the strongest antioxidant ever found. Its antioxidant effect is 1000 times that of vitamin E, and it is widely used in the international first-line cosmetics, health food, and pharmaceutical fields. Studies have shown that astaxanthin can significantly inhibit brain lipid peroxidation such as chemotherapy (cobalt 60 irradiates the brain).

The invention research from Japan Kiso Yoshinobu confirmed that astaxanthin has the ability to normalize the circadian rhythm of living organisms, can effectively increase endogenous melatonin, regulate jet lag, and obtained a patent: EP1283038,

Jet lag can be adjusted by ingesting astaxanthin or [astaxanthin + melatonin]. Vitamin E has no such effect. This effect can be attributed to the powerful antioxidant effect of astaxanthin, as melatonin is easily oxidized by oxidizing factors in the body.

It is also pointed out that the recommended dosage of astaxanthin for adjusting jet lag is 25-50 mg / day, which varies from person to person.

Subsequent research from other institutions has confirmed that for nurses who have just started working the night shift, using astaxanthin at 25 mg / day can quickly change the insomnia and fatigue caused by jet lag. Similarly, for people traveling abroad, you can also start using astaxanthin 25-50mg / day one day before boarding the plane, which can effectively avoid jet lag syndrome. Remember to take it half an hour after a meal and avoid smoking.

Leading the study was Dr. Conwood-Joe, of the Department of Anatomy at the University of Bristol, UK, who said in a published article: "I found that it had no effect on language, but some short-term memory was affected. Impact, and for some abstract cognitive abilities is a serious damage. "

The people surveyed were 20 stewardesses, aged 22 to 28. They all had five years of international flight careers and their routes crossed at least seven time zones. According to Dr. Qiao, women are more susceptible to jet lag than men, which is why he excludes men from research.

The results of this study can be extended from the stewardess to all crew members, and passengers who frequently fly across time zones are often affected by jet lag syndrome. Dr. Robert Sack of Oregon Health Sciences University pointed out: "This study shows that rapid jet lag will have a damaging effect on the brain, and this result is completely unexpected.